Assessment of immunogenicity and protective efficiency of multi-epitope antigen-loaded in mannan decorated PLGA nanoparticles against tuberculosis DOI
Yousef Amini, Mona Kabiri, Saeid Amel Jamehdar

et al.

Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Unravelling the complexity of CARPA: a review of emerging advancements in therapeutic strategies DOI

Shubhi Saxena,

Subhi Sharma,

Gourav Kumar

et al.

Archives of Dermatological Research, Journal Year: 2025, Volume and Issue: 317(1)

Published: Feb. 19, 2025

Language: Английский

Citations

0

Recent advances in DNA nanotechnology for cancer detection and therapy: A review DOI

Donya Esmaeilpour,

Matineh Ghomi, Ehsan Nazarzadeh Zare‬

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142136 - 142136

Published: March 1, 2025

Language: Английский

Citations

0

Application and Safety Research of Nanotechnology in Cosmetics: Current Status, Challenges, and Future Prospects DOI
Xuexue Pan,

H.X. Zhou,

Zhirui Li

et al.

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 22, 2025

Language: Английский

Citations

0

Allergy Treatment: A Comprehensive Review of Nanoparticle-based Allergen Immunotherapy DOI Creative Commons
Mabrouk Abo-Zaid, Reem M. Elsapagh,

Nourhan S. Sultan

et al.

Frontiers in Bioscience-Landmark, Journal Year: 2025, Volume and Issue: 30(3)

Published: March 20, 2025

Allergic disorders rising in prevalence globally, affecting a substantial proportion of individuals industrialized nations. The imbalance the immune system, characterized by elevated allergen-specific T helper 2 (Th2) cells and immunoglobulin E (IgE) antibodies, is key factor allergy development. Allergen-specific immunotherapy (AIT) only treatment capable alleviating allergic symptoms, preventing new sensitizations, reducing asthma risk rhinitis patients. Traditional AIT, however, faces challenges such as frequent administration, adverse effects, inconsistent patient outcomes. Nanoparticle-based approaches have emerged promising strategy to enhance AIT. This review explores utilization nanoparticles highlighting their ability interact with system improve therapeutic Various types nanoparticles, including polyesters, polysaccharide polymers, liposomes, protamine-based (NPs), polyanhydrides, been employed adjuvants or carriers AIT’s efficacy safety. Nanoparticles offer advantages allergen protection, improved response modulation, targeted cell delivery, reduced side effects. provides an overview current landscape nanoparticle-based immunotherapy, discussing its potential revolutionize compared traditional immunotherapy.

Language: Английский

Citations

0

Monoclonal Antibodies in Clinical Trials for Breast Cancer Treatment DOI
Rahaman Shaik,

V. Pavani Sai Mounika,

S. Begum

et al.

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

One of the most potent therapeutic and diagnostic agents in contemporary medicine is monoclonal antibody (mAb). mAbs can perform a variety tasks breast cancer (BC), including identifying delivering medications to targets, preventing cell development, suppressing immune system inhibitors directly attacking cells. are one effective options, particularly for HER2, but they have not been well studied their use treating other forms BC, triple negative tumors. Bispecific trispecific created new opportunities more targeted specific efficacy, which has positive impact on viability antigen specificity. They versatile than treatment, emerging as popular option BC. However, limit treatment due certain adverse effects, fever, shaking, exhaustion, headache, nausea, vomiting, rashes, bleeding, difficulty breathing. To examine current prospective future capacities with regard detection present review highlights advantages disadvantages mAb approach.

Language: Английский

Citations

0

Nanotechnology in the Fight against Antimicrobial Resistance: Designing the Next-Generation Therapies DOI

Muhammad Haroon Rehan,

Juber Akhtar,

Anas Islam

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Antimicrobial resistance has created an urgent need for innovative therapeutic strategies beyond conventional antibiotics. Nanotechnology offers a groundbreaking approach to addressing this challenge by providing versatile tools targeted antimicrobial action. This chapter explores the application of nanomaterials in combating multidrug-resistant pathogens. Emphasis is placed on their mechanisms action, such as biofilm disruption, precision drug delivery, and enhancement efficacy. also discusses recent advancements nano-engineered systems pathogen targeting, well role overcoming mechanisms. By shedding light potential limitations nanotechnology therapy, aims present transformative ongoing battle against superbugs.

Language: Английский

Citations

0

Assessment of immunogenicity and protective efficiency of multi-epitope antigen-loaded in mannan decorated PLGA nanoparticles against tuberculosis DOI
Yousef Amini, Mona Kabiri, Saeid Amel Jamehdar

et al.

Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0