A triple-targeting and viscosity-sensitive fluorescence probe for visualization of liver injury and tumor models
Sensors and Actuators B Chemical,
Journal Year:
2025,
Volume and Issue:
unknown, P. 137614 - 137614
Published: March 1, 2025
Language: Английский
Polarity, pH and HClO triple-response fluorescent probe and its application in inflammation models
Ying Liu,
No information about this author
Weiling Yan,
No information about this author
Jingyu Li
No information about this author
et al.
Journal of Molecular Liquids,
Journal Year:
2025,
Volume and Issue:
unknown, P. 126953 - 126953
Published: Jan. 1, 2025
Language: Английский
Multi-component driven fluorescence composite nanospheres coating strategy: Spectral properties, release, tumor imaging and bioactivity evaluation in a simulated gastrointestinal microenvironment
Mengtong Zhang,
No information about this author
Tiantian Chai,
No information about this author
Shuo Wang
No information about this author
et al.
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy,
Journal Year:
2025,
Volume and Issue:
333, P. 125858 - 125858
Published: Feb. 5, 2025
Language: Английский
An Insight to Nanoliposomes as Smart Radiopharmaceutical Delivery Tools for Imaging Atherosclerotic Plaques: Positron Emission Tomography Applications
Reabetswe Sebatana,
No information about this author
Kahwenga D. Kudzai,
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Allan Magura
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et al.
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(2), P. 240 - 240
Published: Feb. 12, 2025
Atherosclerosis
is
a
chronic
progressive
disease
which
known
to
cause
acute
cardiovascular
events
as
well
cerebrovascular
with
high
mortality.
Unlike
many
other
diseases,
atherosclerosis
often
diagnosed
only
after
an
or
fatal
event.
At
present,
the
clinical
problems
of
mainly
involve
difficulty
in
confirming
plaques
identifying
stability
early
phase.
In
recent
years,
development
nanotechnology
has
come
various
advantages
including
non-invasive
imaging
enhancement,
can
be
studied
for
atherosclerosis.
For
targeted
and
treatment,
nanoliposomes
provide
enhanced
stability,
drug
administration,
extended
circulation,
less
toxicity.
This
review
discusses
current
advances
tailored
liposomal
nano-radiopharmaceutical-based
techniques
their
applications
atherosclerotic
plaque
diagnosis.
further
highlights
nano-radiopharmaceutical
localisation
biodistribution-key
processes
pathophysiology
Finally,
this
direction
future
nano-radiopharmaceuticals
potential
tool
assessment
diagnosis
plaque.
Language: Английский
Endoplasmic reticulum (ER)-targeted ratiometric fluorescent probe for visualization of ER-phagy induced by ONOO- and NIR imaging in mice with drug-induced liver injury
Lei Peng,
No information about this author
Ni Wu,
No information about this author
Zhi Yan
No information about this author
et al.
Biosensors and Bioelectronics,
Journal Year:
2025,
Volume and Issue:
283, P. 117525 - 117525
Published: April 28, 2025
Language: Английский
Macrophage Vesicles‐Loaded NIR‐II AIEgens for Precise In Situ Fluorescence Imaging of Atherosclerosis
Zhiheng Luo,
No information about this author
Xipeng Li,
No information about this author
Caifa You
No information about this author
et al.
Small Methods,
Journal Year:
2025,
Volume and Issue:
unknown
Published: June 2, 2025
Precise
diagnosis
of
atherosclerosis
(AS)
is
a
crucial
strategy
for
reducing
acute
cardiovascular
events.
Herein,
macrophage
membrane
(MM)-camouflaged
biomimetic
vesicle
loaded
with
near-infrared-II
(NIR-II)
aggregation-induced
emission
luminogens
(AIEgens)
(P4TT@MM)
proposed
to
achieve
localized
in
vivo
imaging
atherosclerosis.
The
AIEgens
characteristics
P4TT@MM
effectively
compensate
the
fluorescence
intensity
decrease
caused
by
intramolecular
torsional
charge
transfer
(TICT)
effect,
even
foam
cell-rich
lesions.
Benefiting
from
camouflage
MM
and
its
strong
affinity
atherosclerotic
plaques,
enables
precise
targeting
lesion
sites,
successfully
achieving
high-contrast
plaques
carotid
arteries
aortas
AS
mice
model.
Compared
free
P4TT,
NIR-II
increased
140%
152%
aortas,
respectively.
Moreover,
demonstrates
robust
biocompatibility
combined
significant
clinical
translation
potential.
This
study
may
present
promising
tool
AS.
Language: Английский