Unveiling the trending paradigms of synthesis and theranostic biomedical potentials of nano-diamonds (NDs)

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114313 - 114313

Published: March 1, 2025

Language: Английский

Advanced microfluidic systems with temperature modulation for biological applications

Biomicrofluidics, Journal Year: 2025, Volume and Issue: 19(3)

Published: May 1, 2025

Recent advances in microfluidic technology have shown the importance of precise temperature control a wide range biological applications. This perspective review presents comprehensive overview state-of-the-art platforms that utilize thermal modulation for various applications, such as rapid nucleic acid amplification, targeted hyperthermia cancer therapy, and efficient cellular lysis. We detail heating mechanisms-including nanoparticle-driven induction, photothermal conversion, electrothermal approaches (both external on-chip)-and discuss how they are integrated within lab-on-a-chip systems. In parallel, advanced multi-modal sensing methods microfluidics, ranging from conventional sensors to cutting-edge quantum-based techniques using nanodiamond nitrogen-vacancy centers suspended microchannel resonators, highlighted. By integrating capabilities into these platforms, broader applications enabled, including single-cell analysis, metabolic profiling, scalable diagnostics. Looking ahead, overcoming challenges system integration, scalability, cost-effectiveness will be essential harnessing their full potential. Future developments this field expected drive evolution technologies, ultimately enabling breakthroughs precision medicine high-throughput biomedical

Language: Английский

Nanocomposite Hydrogels from Nanodiamonds and a Self-Assembling Tripeptide

Published: Aug. 8, 2024

We report the successful assembly of a tripeptide in presence nanodiamonds (NDs) into nanocomposite hydrogels. While NDs does not hinder peptide self-assembly and gelation kinetics are affected, improve viscoelastic properties significantly increase elastic moduli Increased resistance gels against applied stress can also be attained depending on amount loaded nanocomposite. Raman micro-spectroscopy TEM confirmed surface, interior, nanofibers. Peptide-ND non-covalent interactions probed by Fourier-transformed infrared spectroscopies. Overall, this work enables embedding hydrogels formed through simple at physiological pH, it provides key insights to open way for their future applications biomaterials, instance exploiting luminescence near-infrared responsiveness.

Language: Английский