Electrochemical Three-Component C–H Functionalization of Indoles with Sodium Bisulfite and Alcohols to Access Indole-Containing Sulfonate Esters DOI
Wei Zhou, Peng Chen, Xiaoqing Xie

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Herein, an efficient electrochemical three-component C-H functionalization of indoles with sodium bisulfite and alcohols is described, providing a sustainable convenient synthetic route for the construction structurally valuable indole-containing sulfonate esters in moderate to good yields. This protocol proceeds undivided cell without any metal catalysts or oxidants, features broad substrate scope, has excellent functional group tolerance. Preliminary mechanistic studies suggest that radical-radical pathway may be involved this reaction system.

Language: Английский

Recent advances in the synthesis and transformations of sulfinate esters DOI Creative Commons
Suguru Yoshida

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Recent sulfinate esters chemistry is summarized in this feature article. Efficient methods to synthesize diverse from readily available starting materials and various modern transformations of are introduced.

Language: Английский

Citations

0
Electrochemical Three-Component C–H Functionalization of Indoles with Sodium Bisulfite and Alcohols to Access Indole-Containing Sulfonate Esters DOI
Wei Zhou, Peng Chen, Xiaoqing Xie

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Herein, an efficient electrochemical three-component C-H functionalization of indoles with sodium bisulfite and alcohols is described, providing a sustainable convenient synthetic route for the construction structurally valuable indole-containing sulfonate esters in moderate to good yields. This protocol proceeds undivided cell without any metal catalysts or oxidants, features broad substrate scope, has excellent functional group tolerance. Preliminary mechanistic studies suggest that radical-radical pathway may be involved this reaction system.

Language: Английский

Citations

0