Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract We present a novel and highly efficient method for synthesizing polyfunctionalized 1,2,4‐triazoles. This approach leverages visible light arylazo sulfones in combination with N ‐vinyl amides, the environmentally friendly solvent ethyl acetate. Remarkably, reaction proceeds without need (photo)catalysts, ensuring near‐perfect atom economy producing only water as by‐product. exhibits excellent functional group tolerance can be scaled both batch continuous‐flow processes.

Language: Английский