An N-linked imidazo[1,2-a]pyridine benzoheterobicyclic hybrid inhibits mitosis and cancer cell proliferation by targeting tubulin DOI
Tuhin Subhra Sarkar,

Mehak Sood,

Shweta Shyam Prassanawar

et al.

Bioorganic & Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 128, P. 118242 - 118242

Published: May 15, 2025

Language: Английский

A Regioselective Ruthenium‐Catalyzed Oxidative C–H Alkenylation of 2‐Aryl‐4H‐Benzo[d][1,3] Oxazin‐4‐Ones DOI

Sepideh Bahrami Nasab,

Seyed Iman Alavioon

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(6)

Published: May 2, 2025

ABSTRACT 2‐Aryl‐ 4H ‐benzo[ d ][ 1 , 3 ]oxazin‐ 4 ‐one derivatives can be directly alkenylated with alkyl acrylates using a facile Ru (II)‐catalyzed process; Cu (OAc) 2 •H O as an oxidizer through formation of pentagon cyclic complex imine‐Ru (II) for C–H activation is described. The unique catalytic reaction well matched miscellaneous olefins such vinyl ketones, acrylonitrile, and acrylates. aryl rings bearing electronically diverse substituents tolerated the conditions to provide ortho‐alkenylation products in high regioselectivities admissible yields.

Language: Английский

Citations

0
An N-linked imidazo[1,2-a]pyridine benzoheterobicyclic hybrid inhibits mitosis and cancer cell proliferation by targeting tubulin DOI
Tuhin Subhra Sarkar,

Mehak Sood,

Shweta Shyam Prassanawar

et al.

Bioorganic & Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 128, P. 118242 - 118242

Published: May 15, 2025

Language: Английский

Citations

0