Cu(II)‐Catalyzed Annulation of o‐Phenylenediamines and Phenacyl Bromides for the Facile Synthesis of 2‐Functionalized Quinoxalines DOI
Yongchao Wang, Yu Chen,

Z. XIONG

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(18)

Published: May 1, 2025

Abstract A facile Cu(II)‐catalyzed annulation of o ‐phenylenediamine and phenacyl bromides in EtOH has been developed. In this protocol, diverse 2‐functionalized quinoxalines were prepared 74%–91% yields with high chemoselectivity. The salient features are the excellent yields, broad substrate scope, mild reaction conditions, large‐scale preparation. This not only fills gap conventional metal‐catalyzed o‐phenylenediamine but also provides a practical strategy for construction quinoxalines.

Language: Английский

Cu(II)‐Catalyzed Annulation of o‐Phenylenediamines and Phenacyl Bromides for the Facile Synthesis of 2‐Functionalized Quinoxalines DOI
Yongchao Wang, Yu Chen,

Z. XIONG

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(18)

Published: May 1, 2025

Abstract A facile Cu(II)‐catalyzed annulation of o ‐phenylenediamine and phenacyl bromides in EtOH has been developed. In this protocol, diverse 2‐functionalized quinoxalines were prepared 74%–91% yields with high chemoselectivity. The salient features are the excellent yields, broad substrate scope, mild reaction conditions, large‐scale preparation. This not only fills gap conventional metal‐catalyzed o‐phenylenediamine but also provides a practical strategy for construction quinoxalines.

Language: Английский

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