Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists DOI Creative Commons
Martijn Dijkstra, Michael Gutmann,

Mathias Gradl

et al.

Inorganic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

An oxaliplatin( iv )-maleimide prodrug containing the STING agonist MSA-2 was synthesized with improved pharmacological properties and diminished hematotoxicity. The complex exerted anticancer effects but did not outperform free oxaliplatin or MSA-2.

Language: Английский

Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists DOI Creative Commons
Martijn Dijkstra, Michael Gutmann,

Mathias Gradl

et al.

Inorganic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

An oxaliplatin( iv )-maleimide prodrug containing the STING agonist MSA-2 was synthesized with improved pharmacological properties and diminished hematotoxicity. The complex exerted anticancer effects but did not outperform free oxaliplatin or MSA-2.

Language: Английский

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