Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy DOI
Junjie Zhang, Zilu Liu, Zhijing Zhang

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(11), P. 7133 - 7169

Published: Nov. 4, 2024

Cancer remains a formidable challenge, inflicting profound physical, psychological, and financial burdens on patients. In this context, silica-based nanomaterials have garnered significant attention for their potential in tumor imaging therapy owing to exceptional properties, such as biocompatibility, customizable porosity, versatile functionalization capabilities. This review meticulously examines the latest advancements application of therapy. It underscores enhancing various cancer modalities, including fluorescence imaging, magnetic resonance computed tomography, positron emission ultrasound multimodal approaches. Moreover, delves into therapeutic efficacy chemotherapy, radiotherapy, phototherapy, immunotherapy, gas therapy, sonodynamic chemodynamic starvation gene Critical evaluations biosafety profiles degradation pathways these within biological environments are also presented. By discussing current challenges prospects, aims provide nuanced perspective clinical translation nanomaterials, thereby highlighting promise revolutionizing diagnostics, enabling real-time monitoring responses, advancing personalized medicine.

Language: Английский

Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy DOI
Junjie Zhang, Zilu Liu, Zhijing Zhang

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(11), P. 7133 - 7169

Published: Nov. 4, 2024

Cancer remains a formidable challenge, inflicting profound physical, psychological, and financial burdens on patients. In this context, silica-based nanomaterials have garnered significant attention for their potential in tumor imaging therapy owing to exceptional properties, such as biocompatibility, customizable porosity, versatile functionalization capabilities. This review meticulously examines the latest advancements application of therapy. It underscores enhancing various cancer modalities, including fluorescence imaging, magnetic resonance computed tomography, positron emission ultrasound multimodal approaches. Moreover, delves into therapeutic efficacy chemotherapy, radiotherapy, phototherapy, immunotherapy, gas therapy, sonodynamic chemodynamic starvation gene Critical evaluations biosafety profiles degradation pathways these within biological environments are also presented. By discussing current challenges prospects, aims provide nuanced perspective clinical translation nanomaterials, thereby highlighting promise revolutionizing diagnostics, enabling real-time monitoring responses, advancing personalized medicine.

Language: Английский

Citations

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