Organic Letters, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 25, 2024
Easily obtainable and efficient chiral
Language: Английский
Organic Letters, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 25, 2024
Easily obtainable and efficient chiral
Language: Английский
ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(41)
Published: Oct. 28, 2024
Abstract We are reporting a convenient method for the synthesis of bis(indolyl)methane derivatives from relatively cheap and commercially available chemicals such as indoles aldehydes in one‐pot procedure using Ga‐MCM‐41‐SO 3 H heterogeneous catalyst. Notably, use this catalyst has resulted high yield products (up to 98 %) under mild conditions, was found be stable reusable, retaining its highly catalytic activity even after five runs. Interestingly, two alkaloids Arsindoline A Turbomycine B were successfully synthesized employment These findings suggest that could promising alternative traditional acid homogeneous catalysts derivatives, offering several advantages including ease separation reuse, stability, low toxicity.
Language: Английский
Citations
0Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Comprehensive Summary Terpyridine ligands have been applied as a class of unique due to their rich coordination chemistry in the catalysis. Herein, we developed new C 2 ‐symmetric chiral terpyridine‐pyrroloimidazolone (TPy‐BPI). Their catalytic activity was evaluated asymmetric Friedel‐Crafts alkylation indoles with 2,3‐dioxopyrrolidines. Excellent yields (up 92%) and high enantioselectivities 97% ee) are obtained for wide range substrates under mild conditions. In addition 2,3‐dioxopyrrolidines, β , γ ‐unsaturated α ‐ketoesters were also compatible Ni(OTf) ‐TPy‐BPI ligand L1 ‐catalyzed reaction. Control experiments, single crystal structure two TPy‐BPI ‐Ni(OTf) complexes, DFT calculations revealed origins enantioselectivity. To best our knowledge, work is first report showing that terpyridine framework contained only nitrogen atoms coordinating metal, additional pyridine unit acted stereodirecting element, which different from previously reported containing all three metal.
Language: Английский
Citations
0Organic Letters, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 25, 2024
Easily obtainable and efficient chiral
Language: Английский
Citations
0