Asian Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 28, 2025

Abstract Herein, an efficient method for the synthesis of 5‐arylselenyluracils via bromide‐catalyzed selective C( sp 2 )‐H selenylation uracils using boronic acid and elemental selenium as selenyl source was successfully developed. This proceeded smoothly a series arylboronic acids under metal‐free strong oxidant‐free conditions. protocol offered simple catalytic conditions, high efficiency, good functional group compatibility, easy operation, scalable. Furthermore, mechanistic studies suggested that this transformation possibly undergone radical pathway.

Language: Английский