Visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N3 via electrondonor–acceptor complexes DOI
Peng Xie, Yue Gao,

Chenqi Wu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

A visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N 3 toward a series azidated pyrrolo[1,2- ]indoles via an EDA complex as the key intermediate.

Language: Английский

Visible-light-promoted trifluoromethylation/arylation of unactivated alkenes with Togni-CF3 for the synthesis of trifluoromethylated pyrrolo[1,2–a]indoles DOI

Hongni Qin,

Yong Zhang, Song Sun

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: unknown, P. 155468 - 155468

Published: Jan. 1, 2025

Language: Английский

Citations

0
Photochemical aerobic sulfonylation–cyclization–selenylation to indole-fused medium-sized N-heterocycles in 2-Me-THF DOI

Tongtong Shi,

Miao Tian,

Zongfei Sun

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We report a novel visible-light-induced sulfonylation cyclization and aerobic selenylation reaction for the rapid construction of highly functionalized indole-fused medium-sized diazepinones with biomass feedstock 2-Me-THF as medium.

Language: Английский

Citations

0
From S-Fluoroalkylation to Fluoroalkylation–Thiolation: Difunctionalization of Alkenes with Fluoroalkyl Phenyl Sulfones and Thiophenols Enabled by Photoredox Copper Catalysis DOI
Xiao Lin, Zhiqiang Wei, Chuanfa Ni

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

Molecules containing fluoroalkyl and arylthio groups play a pivotal role in pharmaceutical agrochemical development. The simultaneous introduction of these functional through the 1,2-difunctionalization alkenes is an efficient strategy. Fluoroalkyl phenyl sulfones serve as accessible radical precursors; however, their tendency to interact with thiophenol via electron donor–acceptor interaction mechanism can impede desired transformation. Through meticulous selection solvent base, we successfully utilized copper catalysis facilitate alkene-involved three-component reaction. Our work unveils photoredox copper-catalyzed fluoroalkylation–thiolation using various (such perfluoroethyl, tetrafluoroethyl, trifluoromethyl, difluoromethyl, difluoroalkyl, difluorobenzyl). efficacy this approach exemplified by synthesis Kengreal derivatives.

Language: Английский

Citations

0
Photo-induced decarboxylative radical cascade cyclization of unactivated alkenes: access to CF- and CF2-substituted ring-fused imidazoles DOI Creative Commons
Hui-Nan Wang, Shaohui Lin, Hui Hong

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(16), P. 12739 - 12745

Published: Jan. 1, 2025

A mild and effective visible-light-induced decarboxylative radical cascade reaction of olefin-containing imidazoles α-fluorinated carboxylic acids, has been developed to afford monofluoromethylated or aryldifluoromethylated polycyclic imidazoles.

Language: Английский

Citations

0
Visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N3 via electrondonor–acceptor complexes DOI
Peng Xie, Yue Gao,

Chenqi Wu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

A visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N 3 toward a series azidated pyrrolo[1,2- ]indoles via an EDA complex as the key intermediate.

Language: Английский

Citations

0