Molecular Engineering of Red Aggregation-Induced Emission Luminogens with Small Conjugated Structures DOI

Ziqiong Huang,

Jufang Yang,

Jianshuo Cheng

et al.

Chemistry of Materials, Journal Year: 2024, Volume and Issue: 36(17), P. 8546 - 8554

Published: Aug. 20, 2024

Design strategies for red/near-infrared aggregation-induced emission luminogens (AIE-gens) with biological applications still face significant challenges as the conventional π-conjugated extension requires complex synthesis routes and usually suffers from poor solubility. Herein, we propose a delicate strategy red through AIE of small conjugated structures, hexaselenobenzene derivatives (6SeBA 6SeBPI), assistance heavy atom effect substitution selenium. The core exhibits both efficient triplet-state emission. Through molecular engineering, 6SeBA bright stable photoluminescence at 650 nm large Stokes shift, 6SeBPI shows dual bands, further demonstrating dynamical monitoring cellular processes via multichannel imaging. In addition, can generate greater quantity reactive oxygen species upon exposure to light, thereby conferring potential photodynamic immunotherapy. This provides insights into design shorter scales, paving way simultaneous imaging therapy.

Language: Английский

Molecular Engineering of Red Aggregation-Induced Emission Luminogens with Small Conjugated Structures DOI

Ziqiong Huang,

Jufang Yang,

Jianshuo Cheng

et al.

Chemistry of Materials, Journal Year: 2024, Volume and Issue: 36(17), P. 8546 - 8554

Published: Aug. 20, 2024

Design strategies for red/near-infrared aggregation-induced emission luminogens (AIE-gens) with biological applications still face significant challenges as the conventional π-conjugated extension requires complex synthesis routes and usually suffers from poor solubility. Herein, we propose a delicate strategy red through AIE of small conjugated structures, hexaselenobenzene derivatives (6SeBA 6SeBPI), assistance heavy atom effect substitution selenium. The core exhibits both efficient triplet-state emission. Through molecular engineering, 6SeBA bright stable photoluminescence at 650 nm large Stokes shift, 6SeBPI shows dual bands, further demonstrating dynamical monitoring cellular processes via multichannel imaging. In addition, can generate greater quantity reactive oxygen species upon exposure to light, thereby conferring potential photodynamic immunotherapy. This provides insights into design shorter scales, paving way simultaneous imaging therapy.

Language: Английский

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