Journal of Food Science and Technology, Journal Year: 2024, Volume and Issue: 62(2), P. 240 - 253
Published: Nov. 22, 2024
Language: Английский
Polymer Bulletin, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 30, 2024
Language: Английский
Citations
10
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137318 - 137318
Published: Nov. 14, 2024
Language: Английский
Citations
7
Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126541 - 126541
Published: Nov. 1, 2024
Language: Английский
Citations
4
Applied Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 1145 - 1145
Published: Jan. 23, 2025
Guided tissue regeneration (GTR) membranes are pivotal in regenerative medicine. While their effectiveness is established general populations, application immunocompromised patients, such as those with diabetes or cancer, remains underexplored. This review evaluated evidence on GTR settings, focusing mechanisms, outcomes, and challenges posed by systemic conditions. A systematic search identified studies use these populations. Inclusion criteria were peer-reviewed articles English human samples relevant preclinical models. Of 218 articles, 5 met the criteria. These highlighted advancements technologies, stem cell integration, growth factor-enriched scaffolds, scaffold-free engineering. Stem cell-based approaches improved regeneration, especially biomimetic designs incorporating bone morphogenetic protein-2. Innovations like microcavity-rich scaffolds enhanced angiogenesis osteogenesis, while constructs minimized immunogenicity supported functional regeneration. Preclinical models demonstrated membranes’ potential for addressing large-scale deficits compromised environments. show promise but further research needed to validate clinical efficacy, address patient-specific challenges, evaluate long-term outcomes. technologies could transform medicine, providing sustainable solutions high-risk
Language: Английский
Citations
0
Journal of Biomaterials Science Polymer Edition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24
Published: Feb. 18, 2025
The science of Bone tissue engineering (TE) is quickly progressing. Engineering bone usually applications a synthetic extracellular matrix, cells or osteoblasts that can convert to osteoblasts, and adjusting causes boost adhesion, distinction, mineralized construction cells. Extremely porous scaffolds perform an important character in cell planting, propagation, fresh 3D-tissue construction. Reformative medicine track multi-disciplinary approach for the novel substances' development appliance, various defects therapy. presentation polyhedral oligomeric silsesquioxane (POSS) bio-polymeric scaffold has been shown develop biotic attributes hybrid combinations. This review focuses on influence POSS within Chitosan (CS), Hydroxyapatite (HA), zeolite matrixes, drawing, advantages limitations materials mentioned bone.
Language: Английский
Citations
0
Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1276 - 1276
Published: March 12, 2025
Biopolymeric drug delivery systems enhance the bioavailability and therapeutic efficacy of poorly soluble bioactive compounds. In this study, chitosan (Chi), dextran (Dex), carboxymethyl (mDex), lignin (L), curcumin (Cu) were combined to develop materials with controlled release, antioxidant, anti-inflammatory properties. The mechanical evaluation showed that Chi-mDex-L-Cu exhibited highest diametral tensile strength (2.40 MPa), a 1233% increase compared Chi-mDex-L, due strong hydrogen bonding interactions between matrix components. Curcumin release kinetics, modeled using Weibull equation, demonstrated presented slowest rate, reducing cumulative by 55.66% as Chi-L-Cu, ensuring prolonged bioactivity. Despite its retained 60% antioxidant 70% activity, making it promising sustained-release system. biocompatibility assessment confirmed cell viability above 85%, showing slight (~10%) reduction at higher concentrations while remaining non-cytotoxic. These findings suggest is candidate for biomedical applications requiring effects, such osteoarthritis treatment.
Language: Английский
Citations
0
Ceramics International, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
Macromolecular Research, Journal Year: 2025, Volume and Issue: unknown
Published: April 11, 2025
Language: Английский
Citations
0
Published: April 24, 2025
This review highlights the challenges of current wound healing methods, such as scar formation and limited regeneration, emphasizes potential tissue engineering to address these issues. Chitosan, a biopolymer derived from chitin, has garnered significant attention in epidermal-dermal due its exceptional biocompatibility, biodegradability, versatile functional properties. article delves into diverse roles chitosan, with particular focus on use scaffold material fine-tunable physicochemical biological properties for accelerated healing. While bare chitosan provides suitable microenvironment cell adhesion proliferation, it exhibits mechanical strength drug-delivery However, combining other natural synthetic polymers nanoparticles facilitates drug biosignal delivery enhances biocompatibility antibacterial activity. Furthermore, covers various chemical modifications including quaternization methacrylation, improve water solubility strength, developing advanced dressings effective skin regeneration. The also discusses types smart hydrogels clinical translation based scaffolds regeneration applications. Finally, integration 3D bioprinting techniques creating complex, cell-incorporated therapies.
Language: Английский
Citations
0
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Citations
0