Doping Detection Based on the Nanoscale: Biosensing Mechanisms and Applications of Two-Dimensional Materials

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 227 - 227

Published: April 3, 2025

Doping undermines fairness in sports and threatens athlete health, while conventional detection methods like LC-MS GC-MS face challenges such as complex procedures, matrix interferences, lengthy processing times, limiting on-site applications. Two-dimensional (2D) materials, including graphene, MoS2, metal–organic frameworks (MOFs), offer promising solutions due to their large surface areas, tunable electronic structures, special interactions with doping agents, hydrogen bonding, π-π stacking, electrostatic forces. These materials enable signal transduction through changes conductivity or fluorescence quenching. This review highlights the use of 2D detection. For example, reduced graphene oxide–MOF composites show high sensitivity for detecting anabolic steroids testosterone, NiO/NGO nanocomposites exhibit strong selectivity stimulants ephedrine. However, environmental instability production costs hinder widespread application. Future efforts should focus on improving material stability chemical modifications, reducing costs, integrating these into advanced systems machine learning. Such advancements could revolutionize detection, ensuring protecting health.

Language: Английский

Continuous synthesis of PEGylated MIL-101(Cr) nanoparticles for neuroprotection

RSC Advances, Journal Year: 2025, Volume and Issue: 15(15), P. 12020 - 12027

Published: Jan. 1, 2025

A method that combines continuous flow and ultrasound was established for the synthesis of MOF nanoparticles with bioactive ligand to mitigate nervous system injury.

Language: Английский