Multifunctional Polyoxovanadate-Based Covalent Organic Polymer for Bacteria-Infected Wound Therapy DOI
Yinuo Li, Liyan Zhao,

Manli Liu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

The special pathological microenvironment of infected wounds (pathology weakly acidic, hypoxic, and overexpressed H2O2) provides fertile soil for the development disease. Tailoring treatment based on specific characteristics infectious (IME) has emerged as a novel direction in antimicrobial therapies. Here, polyoxovanadate (POV)-based covalent organic polymer (POV-Fc-COP) with inherent photothermal activity was facilely prepared via copolymerization 1,1′-bi(3-dimethylamino-1-oxo-2-enyl-ferrocene) (BDOEF) tris-NH2-modified POV (tris-V6O9), which nanovanadium oxide (V2O3 V2O5) core shell were generated directly during Michael addition–elimination reaction. unique structure composition impart pH-responsive peroxidase-like (POD-like) catalase-like (CAT-like) activities, concurrently, to POV-Fc-COP. Specifically, acid-activated mimicking-POD could consume H2O2 microenvironment, producing toxic •OH combat bacteria biofilms. vanadium consumes excessive acid, resulting an increase pH. Meanwhile, CAT-like transform excess expression into O2 relieve hypoxia induced by damage blood vessels facilitate wound healing. Additionally, synergistic amplified therapeutic effect triggered application laser irradiation facilitates rapid eradication biofilm, minimizing detrimental impacts bacterial proliferation IME, thereby accelerating restoration IME return normal state. Therefore, POV-Fc-COP dual-enzyme functionality not only utilize but also regulate significantly expediting healing bacteria-infected wounds. This study demonstrates simple method preparation intelligent platform programmed antibacterial antibiofilm formation, thus promoting while utilizing improving IME.

Language: Английский

Photocatalytic Decarboxylative Fluorination by Quinone-Based Isoreticular Covalent Organic Frameworks DOI
Ayan Jati, Ashok Kumar Mahato,

Durba Chanda

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(34), P. 23923 - 23932

Published: Aug. 16, 2024

The strategic incorporation of fluorine atoms into molecules has become a cornerstone modern pharmaceuticals, agrochemicals, and materials science. Herein, we have developed covalent organic framework (COF)-based, robust photocatalyst that enables the photofluorodecarboxylation reaction diverse carboxylic acids, producing alkyl fluorides with remarkable efficiency. catalytic activity an anthraquinone-based COF catalyst

Language: Английский

Citations

11
Photocatalytic Applications of Covalent Organic Frameworks: Synthesis, Characterization, and Utility DOI Creative Commons

Jared G. Doremus,

Bertha Lotsi,

Amit Sharma

et al.

Nanoscale, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This review highlights the recent advances in utilizing covalent organic frameworks (COFs) for photocatalytic applications.

Language: Английский

Citations

5
Hydrogen radical-driven anthraquinone- promoted H2O2 photosynthesis DOI
Miao Qi,

Zi-jie Cao,

Yixian Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160957 - 160957

Published: Feb. 1, 2025

Language: Английский

Citations

0
Effect of π-Linkages in Covalent Organic Framework-Catalyzed Light-Harvesting Thioesterification Reaction DOI
Ayan Jati,

Durba Chanda,

Biplab Maji

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Covalent organic frameworks (COFs) serve as an outstanding platform for heterogeneous photocatalysis. We synthesized two analogous pyrene-based two-dimensional COFs with π-conjugated networks, one linked by C═N bonds and the other C═C bonds, through Schiff base Knoevenagel condensation reactions, respectively. investigated impact of these linkages on photocatalytic activity COFs, using visible-light-mediated thioesterification a model reaction. It was found that olefin-linkage COF outperformed imine-linkage photocatalyst. The developed protocol demonstrated broad substrate scope, including 35 diverse carboxylic acids, 14 drug molecules, several disulfide coupling partners, achieving up to 95% yield thioesters. practical utility this strategy is further its successful application in gram-scale reactions. photocatalyst robust successfully reused multiple cycles without any loss catalytic activity. backbone facilitated enhanced electron transfer upon light irradiation, enabling cross-coupling acid reductive cycle.

Language: Английский

Citations

0
A Universal Approach to Anchoring Chromophores onto Magnetic Scaffold for Achieving Easily Recyclable Heterogeneous Photocatalytic Systems DOI Creative Commons
Xuan Zhan, Yikun Wang, Chenyang Sun

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Photocatalysis based on chromophores such as porphyrin, coumarin, anthraquinone, and pyrene is a promising technology to achieve green synthesis of various high-value chemicals, but the robust non-covalent immobilization onto light-inert scaffolds for industrialization-oriented heterogeneous photocatalysis remains challenging. In this work, simple universal strategy presented preparing highly efficient recyclable photocatalysts from chromophores, which achieved via biotinylation chromophore molecules subsequent supramolecular binding chromophore-biotin dyads streptavidin-decorated magnetic beads. As an example, commercial beads modified by 5,10,15,20-tetrakis(4-aminophenyl) porphyrin not only possessed remarkable photocatalytic activities oxidative coupling benzylamine derivatives oxidation thioanisole with highest product yields beyond 95% turnover numbers approaching 10000, driven photogenerated reactive oxygen species also demonstrated impressive chemical stability recyclability separation during 10 successive test cycles. The findings revealed in work pave way advancing valuable organic compounds pharmaceutical industry, agricultural sector, etc., rationally designed systems.

Language: Английский

Citations

0
Photochemically Stable Amide-Linked Covalent Organic Framework for Efficient Dual Photoredox and Copper Catalysis DOI

Zhi‐Bei Zhou,

Yingjie Fan,

Abigail L. Blenko

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 8724 - 8732

Published: May 8, 2025

Language: Английский

Citations

0
An Anthraquinone-Based COF: A Direct Hydrogen-Atom Transfer Photocatalyst for C–N/C–C Couplings DOI
Yasuhiro Uozumi, Kaili Zhang

Synfacts, Journal Year: 2024, Volume and Issue: 20(07), P. 0736 - 0736

Published: June 14, 2024

Key words photocatalysis - C–N/C–C cross-coupling anthraquinone-based COF

Language: Английский

Citations

0
Multifunctional Polyoxovanadate-Based Covalent Organic Polymer for Bacteria-Infected Wound Therapy DOI
Yinuo Li, Liyan Zhao,

Manli Liu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

The special pathological microenvironment of infected wounds (pathology weakly acidic, hypoxic, and overexpressed H2O2) provides fertile soil for the development disease. Tailoring treatment based on specific characteristics infectious (IME) has emerged as a novel direction in antimicrobial therapies. Here, polyoxovanadate (POV)-based covalent organic polymer (POV-Fc-COP) with inherent photothermal activity was facilely prepared via copolymerization 1,1′-bi(3-dimethylamino-1-oxo-2-enyl-ferrocene) (BDOEF) tris-NH2-modified POV (tris-V6O9), which nanovanadium oxide (V2O3 V2O5) core shell were generated directly during Michael addition–elimination reaction. unique structure composition impart pH-responsive peroxidase-like (POD-like) catalase-like (CAT-like) activities, concurrently, to POV-Fc-COP. Specifically, acid-activated mimicking-POD could consume H2O2 microenvironment, producing toxic •OH combat bacteria biofilms. vanadium consumes excessive acid, resulting an increase pH. Meanwhile, CAT-like transform excess expression into O2 relieve hypoxia induced by damage blood vessels facilitate wound healing. Additionally, synergistic amplified therapeutic effect triggered application laser irradiation facilitates rapid eradication biofilm, minimizing detrimental impacts bacterial proliferation IME, thereby accelerating restoration IME return normal state. Therefore, POV-Fc-COP dual-enzyme functionality not only utilize but also regulate significantly expediting healing bacteria-infected wounds. This study demonstrates simple method preparation intelligent platform programmed antibacterial antibiofilm formation, thus promoting while utilizing improving IME.

Language: Английский

Citations

0