Virulence factors and therapeutic methods of Trueperella pyogenes : A review

Virulence, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 21, 2025

Trueperella pyogenes is a prevalent opportunistic pathogen responsible for wide range of infections in livestock and wildlife, such as cattle, pigs, European bison forest musk deer. Much the successful infection T. relies on its virulence factors, including pyolysin well adhesion factors. The swift rise bacterial resistance has highlighted urgent need developing new therapeutic strategies. Currently, factor-mediated vaccine development other approaches are widely regarded primary interventions addressing diseases associated with this pathogen. This review examines broader potential pyogenes, focusing haemolysin, host cell proteins, prevalence antibiotic resistance, vaccines mediated by Additionally, it discusses current future aimed at improving interventions.

Language: Английский

ZnI2-Mediated cis-Glycosylations of Various Constrained Glycosyl Donors: Recent Advances in cis-Selective Glycosylations

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4710 - 4710

Published: Oct. 4, 2024

An efficient and versatile glycosylation methodology is crucial for the systematic synthesis of oligosaccharides glycoconjugates. A direct intermolecular an indirect intramolecular have been developed, former can be applied to medium-to-long-chain glycans like that nucleotides peptides. The development a generally applicable approach stereoselective construction glycosidic bonds remains major challenge, especially 1,2-

Language: Английский