Recent Advances in Electrochemical Affinity Biosensors: Detection of Biological Toxin Agents DOI

Doga Ekin Orhan,

Manolya Müjgan Yıldız,

Eda Nur Aybi

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: May 19, 2025

Biological toxins are metabolic products produced by living organisms. They exert deleterious effects on another organism through food, drinking water, inhalation, injection, ingestion, and absorption the skin or mucous membranes. Health such as respiratory distress, muscle weakness, seizures, paralysis, death depend amount route of exposure to toxins. act quickly fatal even in low doses, can be considered bioterror agents due their high potency, reasonably long latency period before symptoms exhibited, difficulty detecting diagnosing presence identity, relative ease production stability environment. The development selective sensitive electrochemical biosensors has been main importance for quantification biological amounts samples. This review examined detection various toxin using aptasensors immunosensors from 2019 2025. study provided information effect mechanism organism, modification affinity biosensors, smartphone-based portable used analysis

Language: Английский

A modularized universal strategy by integrating CRISPR/Cas with nanoporous materials for ultrasensitive determination of nucleic acids DOI

Hongkai Wang,

Yinzheng Niu, Hui Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160065 - 160065

Published: Jan. 1, 2025

Language: Английский

Citations

2

Roles of nanomagnetic beads on biosensing: From fabrication to application DOI Creative Commons
Junjie Li, Lei Duan, Qian Chen

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Abstract As magnetic nanomaterials, nanomagnetic beads are constantly being innovated in various applications. With the advantages of superparamagnetism and rapid response, can be controlled for type movements under external fields, such as fixation, aggregation, or dispersion. Meanwhile, composited with multiple functional materials, therefore, expanding applications biomedical, environmental monitoring, food safety. For example, integration magnetoresistive sensors amplify detection signals through superparamagnetic properties. modification recognition components, function by specifically binding target analytes, serving sensitive elements biosensing. In this review, we firstly summarized fabrication approaches beads, supporting fundamental information their Then, roles field biosensing were systematically discussed, sample preparation, immobilization, signal amplification, detection. Through investigation on biosensing, finally evaluated current bottlenecks development biosensors predicted future opportunities challenges based advancement beads.

Language: Английский

Citations

1

Bioelectroanalytical Technologies for Advancing the Frontiers To Democratize Personalized Desired Health DOI Creative Commons
Susana Campuzano, Víctor Ruiz‐Valdepeñas Montiel, Rebeca M. Torrente‐Rodríguez

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

The breakthroughs experienced in the development of cutting-edge, reliable, and multipurpose (bio)electroanalytical technologies their successful incursion into underexplored scenarios have demonstrated unique potential to act as enablers ongoing transformation from reactive predictive, preventive, personalized, participatory healthcare, currently known "P4" medicine. This transformation, more than a vision, is necessity achieve new generation efficient, sustainable, tailored individual needs healthcare. promising outlook focus this Perspective, which addition highlighting some most shocking related research over last 5 years, offers prospective insightful view opportunities imminent advances that shape future these fascinating technologies.

Language: Английский

Citations

0

Recent Advances in Electrochemical Affinity Biosensors: Detection of Biological Toxin Agents DOI

Doga Ekin Orhan,

Manolya Müjgan Yıldız,

Eda Nur Aybi

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: May 19, 2025

Biological toxins are metabolic products produced by living organisms. They exert deleterious effects on another organism through food, drinking water, inhalation, injection, ingestion, and absorption the skin or mucous membranes. Health such as respiratory distress, muscle weakness, seizures, paralysis, death depend amount route of exposure to toxins. act quickly fatal even in low doses, can be considered bioterror agents due their high potency, reasonably long latency period before symptoms exhibited, difficulty detecting diagnosing presence identity, relative ease production stability environment. The development selective sensitive electrochemical biosensors has been main importance for quantification biological amounts samples. This review examined detection various toxin using aptasensors immunosensors from 2019 2025. study provided information effect mechanism organism, modification affinity biosensors, smartphone-based portable used analysis

Language: Английский

Citations

0