Harnessing the Potential of Graphene Quantum Dots for Multifunctional Biomedical Applications DOI Open Access

Yujia Han,

Hongyan Hao, Huadong Zeng

et al.

The Chemical Record, Journal Year: 2024, Volume and Issue: 24(12)

Published: Nov. 11, 2024

Abstract The existing and emerging demand for materials life health has contributed to the cultivation development of respective markets. Nevertheless, current generation biomedical yet fully satisfy clinical requirements market, which is still in its relative infancy. Research this area must be prioritized light pivotal role new biological field. Among many materials, GQDs, an nanomaterial, exhibit considerable promise field, primarily due their exceptional properties. Furthermore, direct preparation functionalization GQDs have facilitated specific functional composites based on GQDs. applications are undergoing rapid growth, makes it necessary publish a review article presenting latest advances This provides overview significant synthesizing techniques employed structural characterizations, properties that been elucidated. presents recent findings applying antimicrobial, anticancer, biosensing, drug delivery, bioimaging applications. Finally, explores potential biomedicine biotechnology, highlighting challenges remain addressed.

Language: Английский

The role of graphene quantum dots in cutting‐edge medical therapies DOI

Kosar Arab,

Aliakbar Jafari, Farangis Shahi

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(9)

Published: Sept. 1, 2024

Abstract Graphene quantum dots (GQDs), owing to their unique optical, electrical, and chemical properties, have emerged as promising nanomaterials for various biomedical applications. This review provides a comprehensive overview of the latest advancements in utilization GQDs tissue engineering, wound healing, drug delivery systems, other therapies. The inherent properties GQDs, including high biocompatibility, tunable photoluminescence, significant surface area, make them ideal candidates enhancing medical treatments diagnostics. In improve mechanical biological performance scaffolds, promoting cell proliferation differentiation. For enhance antimicrobial activity facilitate faster regeneration. Their potential DDS is highlighted by ability deliver therapeutic agents efficiently, ensuring targeted controlled release. Additionally, play crucial role therapies, particularly cancer treatment, efficacy reducing side effects. While offer diagnostics, challenges such understanding long‐term cytotoxicity at higher concentrations, need standardized synthesis methods remain critical areas further research. also discusses future directions opportunities emphasizing transformative advancing modern healthcare solutions. insights presented here contribute expanding field GQD research, highlighting significantly patient outcomes drive innovations.

Language: Английский

Citations

11
Empowering rapid diagnosis and treatment of glioblastoma with biofunctionalized carbon quantum dots: a review DOI Creative Commons
Kimia Kazemi, Abbas Amini, Navid Omidifar

et al.

Cancer Nanotechnology, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 14, 2025

Language: Английский

Citations

2
Global trends and emerging research in nanotechnology for esophageal cancer: a comprehensive bibliometric analysis DOI Creative Commons

Chunjian Zuo,

Jie Tian

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 3, 2025

Despite the growing body of research on nanotechnology for esophageal cancer (EC), a comprehensive bibliometric analysis in this field has yet to be conducted. This study aims fill gap by analyzing global trends, key contributors, and emerging themes EC. A was performed publications from 1980 2024, using data Web Science Core Collection. The conducted VOSviewer, CiteSpace, R package 'bibliometrix' visualize collaboration networks, thematic areas. included 419 documents authored 2952 researchers 44 countries. significant increase observed, particularly after 2011, with China, United States, Japan leading contributions. Prominent institutions, including Zhengzhou University Chinese Academy Sciences, were identified as players. predominantly focused drug delivery systems, nanomedicine, treatment mechanisms, trends development advanced nanomaterials personalized therapies. applications EC highlights findings underscore crucial role advancing strategies identify areas future interdisciplinary collaboration.

Language: Английский

Citations

1
Dual acid-base catalysis with biologically modified graphene oxide: a sustainable route to polyhydroquinolines with antimicrobial properties DOI Creative Commons
Leila Amiri‐Zirtol, Hamideh Emtiazi, Seyedeh Narjes Abootalebi

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 25, 2025

This article conducts an in-depth examination of graphene oxide-aspartic acid (GO-As) as a novel bifunctional nano-organocatalyst distinguished by both catalytic and antibacterial properties. The research elucidates the synthesis GO through Hummer's method, followed covalent attachment aspartic to surface nanosheets. innovative approach is particularly notable it circumvents use hazardous chemicals, thereby promoting environmental sustainability. newly developed catalyst underwent rigorous analysis employing variety spectroscopic techniques, including Fourier Transform Infrared (FT-IR) spectroscopy, Energy-Dispersive X-ray Spectroscopy (EDX), mapping, Field Emission Scanning Electron Microscopy (SEM), diffraction (XRD), thermogravimetric (TGA), Raman spectroscopy. findings indicate that effectively synthesizes polyhydroquinoline derivatives while demonstrating significant stability over multiple reuse cycles, underscoring its potential applicability in organic synthesis. Furthermore, properties GO-modified were evaluated against six pathogenic bacterial species. results reveal substantial activity Gram-positive Gram-negative strains, two antibiotic-resistant bacteria: Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococcus (VRE), Raman. In conclusion, investigation GO-As heterogeneous represents promising advancement development environmentally friendly effective catalysts with noteworthy characteristics.

Language: Английский

Citations

1
Photodynamic and Sonodynamic Therapy Synergy: Mechanistic Insights and Cellular Responses Against Glioblastoma Multiforme DOI
Swati Sharma,

Geetanjali B. Gone,

Parikshit Roychowdhury

et al.

Journal of drug targeting, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Nov. 18, 2024

Glioblastoma multiforme (GBM), the most aggressive form of brain cancer, poses substantial challenges to effective treatment due its complex and infiltrative nature, making it difficult manage. Photodynamic therapy (PDT) sonodynamic (SDT), have emerged as promising individual options against GBM their least-invasive approach. However, both PDT SDT drawbacks that require careful consideration. A combination using light sound waves has gained attention, offering new avenues overcome from therapies. Sono-photodynamic (SPDT) been used various tumors. Researchers are considering SPDT a favorable alternative conventional therapies for GBM. offers complementary mechanisms action, including production ROS, disruption cellular structures, induction apoptosis, leading enhanced tumor cell death. This review gives an insight about PDT/SDT limitations in need therapy. We try unveil process explore mechanism behind improved SPDT-meditated death cells by focusing on ROS-mediated response occurring result discussing current modifications existing sensitizers optimal use

Language: Английский

Citations

4
Advances in 2D heterostructures for quantum computing applications: A review DOI
Aminul Islam, Safiullah Khan,

Juhi Jannat Mim

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 113980 - 113980

Published: Jan. 1, 2025

Language: Английский

Citations

0
Recent advances in graphene quantum dots: Chemistry of synthesis, surface modifications, and improved properties for biomedical applications DOI
Sujogya Kumar Panda,

K. S. Shalini Devi,

Seiya Tsujimura

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118293 - 118293

Published: May 1, 2025

Language: Английский

Citations

0
Photodynamic therapy in esophageal cancer: trends, innovations, and future directions from a global perspective (1985–2024) DOI Creative Commons
Y. Chen, Feng Guo,

Harish Rao

et al.

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: May 14, 2025

Language: Английский

Citations

0
Harnessing the Potential of Graphene Quantum Dots for Multifunctional Biomedical Applications DOI Open Access

Yujia Han,

Hongyan Hao, Huadong Zeng

et al.

The Chemical Record, Journal Year: 2024, Volume and Issue: 24(12)

Published: Nov. 11, 2024

Abstract The existing and emerging demand for materials life health has contributed to the cultivation development of respective markets. Nevertheless, current generation biomedical yet fully satisfy clinical requirements market, which is still in its relative infancy. Research this area must be prioritized light pivotal role new biological field. Among many materials, GQDs, an nanomaterial, exhibit considerable promise field, primarily due their exceptional properties. Furthermore, direct preparation functionalization GQDs have facilitated specific functional composites based on GQDs. applications are undergoing rapid growth, makes it necessary publish a review article presenting latest advances This provides overview significant synthesizing techniques employed structural characterizations, properties that been elucidated. presents recent findings applying antimicrobial, anticancer, biosensing, drug delivery, bioimaging applications. Finally, explores potential biomedicine biotechnology, highlighting challenges remain addressed.

Language: Английский

Citations

0