Efficient light-induced reactive oxygen species production from a far-red ER-targeting BODIPY dye DOI Creative Commons
Shawn Swavey, Arnaud Quentel,

Matthew Grzesiak

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(52), P. 38796 - 38805

Published: Jan. 1, 2024

Generation of reactive oxygen species (ROS) within the ER evokes stress leading to immunogenic cell death. A red light activated BODIPY dye capable subcellular localization producing high quantum yields ROS is reported. The ability this act as a photodynamic therapy (PDT) agent in breast cancer cells suggests promising organelle-targeted therapeutics.

Language: Английский

Triarylphosphonium BODIPY‐Based [2]Rotaxanes Nanoparticles for Light‐Driven Antibacterial Applications DOI Creative Commons

Greta Sambucari,

Corinne Coutant,

Alessandro Di Michele

et al.

Advanced Optical Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 18, 2025

Abstract Antimicrobial photodynamic therapy (aPDT) is a promising strategy to overcome issues related antibiotic resistance. Here the rationale for designing new photosensitizers described based on functionalization of bodipy dyes with triarylphosphonium rotaxanes, and an in‐depth characterization their photophysical properties, applying different spectroscopic techniques, including ultrafast transient absorption spectroscopy provided. While addition halogen atoms some structures provides them ability efficiently produce singlet oxygen in organic solvents, such property suppressed water, where all investigated compounds aggregate into spherical nanoparticles. The latter, independently presence bromine, demonstrate high photothermal conversion efficiency have been tested as antibacterial therapy, highlighting potential self‐assembled nanostructures developing versatile nanomaterials photomedicine applications.

Language: Английский

Citations

0
Lipophilic quaternary ammonium-functionalized BODIPY photosensitizers for mitochondrial-targeted photodynamic therapy and fluorescence cell imaging DOI

Arrhon Mae Bongo,

Joong‐Youn Shim, Sung Cho

et al.

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 116469 - 116469

Published: May 1, 2025

Language: Английский

Citations

0
Efficient light-induced reactive oxygen species production from a far-red ER-targeting BODIPY dye DOI Creative Commons
Shawn Swavey, Arnaud Quentel,

Matthew Grzesiak

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(52), P. 38796 - 38805

Published: Jan. 1, 2024

Generation of reactive oxygen species (ROS) within the ER evokes stress leading to immunogenic cell death. A red light activated BODIPY dye capable subcellular localization producing high quantum yields ROS is reported. The ability this act as a photodynamic therapy (PDT) agent in breast cancer cells suggests promising organelle-targeted therapeutics.

Language: Английский

Citations

1