Uptake of COVID-19 Vaccines among Pregnant Women: A Systematic Review and Meta-Analysis

Vaccines, Journal Year: 2022, Volume and Issue: 10(5), P. 766 - 766

Published: May 12, 2022

Mass vaccination against COVID-19 is essential to control the pandemic. vaccines are now recommended during pregnancy prevent adverse outcomes. With this review, we aimed evaluate evidence in literature regarding uptake of vaccinations among pregnant women. A comprehensive search was performed PubMed, Medline, Scopus, ProQuest, Web Science, CINAHL, and medRxiv from inception 23 March 2022. We a meta-analysis estimate overall proportion women vaccinated COVID-19. found 11 studies including 703,004 The 27.5% (95% CI: 18.8–37.0%). Predictors were older age, ethnicity, race, trust vaccines, fear pregnancy. Mistrust government, diagnosis pregnancy, fears about safety side effects reasons for declining vaccination. global prevalence low. large gap exists on factors influencing decision be Targeted information campaigns increase vaccine literacy

Language: Английский

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A population-based matched cohort study of major congenital anomalies following COVID-19 vaccination and SARS-CoV-2 infection

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Jan. 6, 2023

Abstract Evidence on associations between COVID-19 vaccination or SARS-CoV-2 infection and the risk of congenital anomalies is limited. Here we report a national, population-based, matched cohort study using linked electronic health records from Scotland (May 2020-April 2022) to estimate association and, separately, six weeks pre-conception 19 days gestation [1] any major anomaly [2] non-genetic anomaly. Mothers vaccinated in this pregnancy exposure period mostly received an mRNA vaccine (73.7% Pfizer-BioNTech BNT162b2 7.9% Moderna mRNA-1273). Of 6731 babies whose mothers were period, 153 had 120 Primary analyses find no (adjusted Odds Ratio [aOR] = 1.01, 95% Confidence Interval [CI] 0.83-1.24) (aOR 1.00, CI 0.81-1.22). also 1.02, 0.66-1.60) 0.94, 0.57-1.54). Findings are robust sensitivity analyses. These data provide reassurance safety vaccination, particular vaccines, just before early pregnancy.

Language: Английский

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The impact of the Covid-19 pandemic on postnatal depression: analysis of three population-based national maternity surveys in England (2014–2020)

The Lancet Regional Health - Europe, Journal Year: 2023, Volume and Issue: 30, P. 100654 - 100654

Published: May 15, 2023

Few studies have evaluated postnatal depression before and during the Covid-19 pandemic using comparable data across time. We used from three national maternity surveys in England to compare prevalence risk factors for pandemic.Analysis was conducted population-based carried out 2014 (n = 4571), 2018 4509), 2020 4611). Weighted estimates (EPDS score ≥13) were compared surveys. Modified Poisson regression estimate adjusted ratios (aRR) association between sociodemographic, pregnancy- birth-related, biopsychosocial factors, depression.Prevalence of increased 10.3% 16.0% (difference +5.7% (95% CI: 4.0-7.4); RR 1.55 1.36-1.77)) 23.9% +7.9% 5.9-9.9); 1.49 1.34-1.66)). Having a long-term mental health problem (aRR range 1.48-2.02), antenatal anxiety 1.73-2.12) 1.44-2.24) associated with depression, whereas satisfaction birth 0.89-0.92) social support 0.73-0.78) decreased pandemic.This analysis indicates that had an important negative impact on women's may accelerated existing trend increasing depression. Risk consistent pandemic. Timely identification, intervention follow-up are key supporting women at risk, it is essential mechanisms strengthened times heightened such as pandemic.NIHR Policy Research Programme.

Language: Английский

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Facilitators and barriers to vaccination uptake in pregnancy: A qualitative systematic review

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(4), P. e0298407 - e0298407

Published: April 19, 2024

Introduction Vaccination during pregnancy protects both the mother and foetus from vaccine-preventable diseases. However, uptake of recommended vaccines (influenza, pertussis, COVID-19) by pregnant women remains low in Europe USA. Understanding reasons for this is crucial to inform strategies increase vaccination rates women. This qualitative systematic review aimed identify barriers facilitators against influenza, pertussis/whooping cough COVID-19 possible rates. Methods We conducted a comprehensive search electronic databases, including Medline, PsycINFO, CINAHL, Web Science, WHO database, Embase grey literature studies that explored vaccine among (PROSPERO CRD42023399488). The was limited published between 2012 2022 high-income countries with established programmes pregnancy. Studies were thematically analysed underwent quality assessment using Joanna Briggs Institute validated critical appraisal tool research. Results Out 2681 articles screened, 28 (n = 1573 participants) eligible inclusion. Five overarching themes emerged relating personal, provider systemic factors. Barriers included concerns about safety efficacy, lack knowledge vaccines’ benefits necessity, fear adverse effects on or perception disease severity. Facilitators recommendations trusted healthcare providers, easy access vaccination, clear communication positive social influences family friends. Strategies increasing strong proactive professionals, provision routine antenatal care, consistent addressing women’s concerns. Conclusion highlights need interventions address identified Recommendation can play significant role promoting uptake, as risk/benefit convenient vaccination. Addressing providing accurate information also important.

Language: Английский

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COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis

Vaccines, Journal Year: 2022, Volume and Issue: 10(12), P. 2055 - 2055

Published: Nov. 30, 2022

Mass vaccination against COVID-19 is necessary to control the pandemic. vaccines are now recommended during pregnancy prevent disease. A systematic review of literature in electronic databases PubMed and EMBASE was performed we aimed investigate attitude documents towards prognostic factors hesitation. meta-analysis also conducted estimate overall percentage pregnant women who were willing be vaccinated or had been COVID-19. total 18 studies included meta-analysis. The acceptance rate among ranged from 17.6% 84.5%. pooled proportion 0.53 (95% CI: 0.44-0.61). Predictors older age, White race, occupational status, higher level education, comorbidities, third trimester pregnancy, influenza vaccination, knowledge about COVID-19, confidence that for safe effective. prevalence low. Targeted information campaigns needed increase vaccine education this population.

Language: Английский

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Interventions to increase vaccination against COVID-19, influenza and pertussis during pregnancy: a systematic review and meta-analysis

Journal of Travel Medicine, Journal Year: 2023, Volume and Issue: 30(8)

Published: Nov. 2, 2023

Abstract Background Pregnant women and their babies face significant risks from three vaccine-preventable diseases: COVID-19, influenza pertussis. However, despite these vaccines’ proven safety effectiveness, uptake during pregnancy remains low. Methods We conducted a systematic review (PROSPERO CRD42023399488; January 2012–December 2022 following PRISMA guidelines) of interventions to increase COVID-19/influenza/pertussis vaccination in pregnancy. searched nine databases, including grey literature. Two independent investigators extracted data; discrepancies were resolved by consensus. Meta-analyses using random-effects models estimate pooled effect sizes. Heterogeneity was assessed the I2 statistics. Results From 2681 articles, we identified 39 relevant studies (n = 168 262 participants) across countries. Fifteen (39%) randomized controlled trials (RCTs); remainder observational cohort, quality-improvement or cross-sectional studies. The quality 18% (7/39) strong. Pooled results vaccine (18 estimates 12 RCTs) showed effective but had small (risk ratio 1.07, 95% CI 1.03, 1.13). pertussis (10 six no clear benefit 0.98, 0.94, 1.03). There RCTs for COVID-19. Interventions addressed ‘three Ps’: patient-, provider- policy-level strategies. At patient level, recommendations healthcare professionals backed text reminders/written information strongly associated with increased uptake, especially tailored face-to-face interventions, which women’s concerns, dispelled myths highlighted benefits. Provider-level included educating about effectiveness reminders offer vaccinations routinely. Policy-level financial incentives, mandatory data fields electronic health records ensuring easy availability vaccinations. Conclusions on increasing vaccination. Training providers promote is crucial could be enhanced utilizing mobile technologies.

Language: Английский

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Attitudes Toward COVID-19 Vaccines Among Pregnant and Recently Pregnant Individuals

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(4), P. e245479 - e245479

Published: April 8, 2024

Importance Pregnant people and infants are at high risk of severe COVID-19 outcomes. Understanding changes in attitudes toward vaccines among pregnant recently is important for public health messaging. Objective To assess attitudinal trends regarding by (1) vaccination status (2) race, ethnicity, language samples Vaccine Safety Datalink (VSD) members from 2021 to 2023. Design, Setting, Participants This cross-sectional surveye study included or the VSD, a collaboration 13 care systems US Centers Disease Control Prevention. Unvaccinated, non-Hispanic Black, Spanish-speaking were oversampled. Wave 1 took place October February 2022, wave 2 November 2022 Data analyzed May September Exposures Self-reported electronic record (EHR)–derived preferred language. Main Outcomes Measures monovalent (wave 1) bivalent Omicron booster 2) vaccines. Sample- response-weighted analyses assessed 3 groupings interest. Results There 1227 respondents; all identified as female, mean (SD) age was 31.7 (5.6) years, 356 (29.0%) Black 555 (45.2%) Hispanic 445 (36.3%) Spanish Response rates 43.5% (652 1500 individuals sampled) 39.5% (575 1456 sampled). Respondents more likely than nonrespondents be White, non-Hispanic, vaccinated per EHR. Overall, 76.8% (95% CI, 71.5%-82.2%) reported vaccinations; respondents had highest weighted proportion with vaccination. Weighted estimates somewhat strongly agreeing that safe decreased who vaccinations (76% vs 50%; χ = 7.8; P < .001), White (72% 43%; 5.4; .02), 53%; 22.8; .002). Conclusions Relevance Decreasing confidence vaccine safety large, diverse insured population concern.

Language: Английский

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COVID-19 Vaccine Knowledge, Attitude, Acceptance and Hesitancy among Pregnancy and Breastfeeding: Systematic Review of Hospital-Based Studies

Vaccines, Journal Year: 2023, Volume and Issue: 11(11), P. 1697 - 1697

Published: Nov. 7, 2023

The risk of unfavourable outcomes for SARS-CoV-2 infection is significant during pregnancy and breastfeeding. Vaccination a safe effective measure to lower this risk. This study aims at reviewing the literature concerning anti-SARS-CoV-2 vaccine's acceptance/hesitancy among pregnant breastfeeding women attending hospital facilities. A systematic review was carried out. Hospital-based observational studies related vaccination acceptance, hesitancy, knowledge attitude were included. Determinants acceptance hesitancy investigated in detail. Quality assessment done via Johann Briggs Institute quality tools. After search, 43 included, 30 which only focused on (total sample 25,862 subjects). Sample size ranged from 109 7017 people. Acceptance vaccine 16% 78.52%; between 91.4% 24.5%. Fear adverse events either woman, child, or both, main driver hesitancy. Other determinants included religious concerns, socioeconomic factors, inadequate information regarding lack trust towards institutions. hospitalized appears be significant, efforts more communication these subjects are required.

Language: Английский

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Association between Perceived Ethnic Discrimination and Receipt of COVID-19 Vaccine in Pregnancy or Postpartum

Journal of Racial and Ethnic Health Disparities, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Language: Английский

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The Impact of Coronavirus Disease 2019 (COVID-19) on Vulnerable Communities

Infectious Disease Clinics of North America, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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