Electrochemical Nickel-Catalyzed Synthesis of Unsymmetrical Diorganyl Selanes from Diaryl Diselanes and Aryl and Alkyl Iodides

Molecules, Journal Year: 2024, Volume and Issue: 29(19), P. 4669 - 4669

Published: Oct. 1, 2024

The synthesis of unsymmetrical diorganyl selanes was accomplished under electrochemical conditions in an undivided cell utilizing a magnesium cathode and carbon anode made out aryl alkyl iodides diselanes. This cross-electrophile coupling (eXEC) using simple nickel catalyst formed situ Ni(acac)2 2,2′-bipyridine DMF at ambient temperatures. reaction showed good functional group compatibility, heteroaryl iodides, such as thiophene or pyridine derivatives, were well accepted.

Language: Английский

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Recent Developments in Selenylation of Alkynes

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

Abstract Alkynes are simple yet important organic feedstocks. The selenylation of alkynes is able to produce complex selenium‐containing compounds in a facile way. Although there some reviews about the alkynes, most them focus on one specific reaction or what types products that can be obtained. There lack attention given various uses different selenium reagents and their mechanisms. This review mainly focuses recent advances (2013–2023) based diverse reagents. Mechanisms how added work will discussed. Different types, including difunctionalization, Se‐annulation, spiro‐cyclization, C−Se coupling, click recorded this review. regioselectivity achieved through mechanisms, radicals, seleniraniums electrophilic cyclization. We hope it do help for future research area.

Language: Английский

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Access to Seleno‐Functionalized Thiazolo[3,2‐a]Pyrimidinones and Pyrimido[2,1‐b][1,3]Thiazinones via Selenocyclization of 2‐Alkenylthiopyrimidinones and Their Fused Analogs

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(36)

Published: Sept. 19, 2024

Abstract The methodology of electrophilic selenylation/cyclization 2‐alkenylthiopyrimidinones and their fused analogs underlies most the reported synthetic approaches to seleno‐functionalized thiazolo[3,2‐ a ]pyrimidinones pyrimido[2,1‐ b ][1,3]thiazinones. We have developed novel implementation this strategy using as reagent phenylselenyl chloride or visible‐light‐induced radical‐generating (PhSe) 2 /CBr 4 system. effect unsaturated substrate structure reaction conditions on selenocyclization regioselectivity has been revealed analyzed in detail. It established that regardless used, 2‐allylthiopyrimidinones react with selenylating agents via 5‐ exo ‐ trig cyclization mainly involving N1 nitrogen atom give selenium‐containing major products. On contrary, 2‐cinnamylthiopyrimidinones is dominated by 6‐ endo mode: it mostly involves six‐membered ring closure at N3 thus leading selenylated ][1,3]thiazinones, regiochemistry governed position nature substituents pyrimidine ring. However, some cinnamylthio‐substituted substrates yield cyclized products LiClO /МеNO system (a sufficiently polar solvent strong electrolyte added).

Language: Английский

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Correctional Case Law: 2004-2005

Criminal Justice Review, Journal Year: 2006, Volume and Issue: 31(2), P. 185 - 204

Published: June 1, 2006

Language: Английский

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