
Published: June 26, 2024
Among the different methods to synthesize amides, radical amidation of suitable acceptors is appealing. In this context, we have developed a methodology for photoinduced Minisci and Giese carbamoylation with readily available formamides. This approach avoids using less atom-efficient carbamoyl precursors (e.g., oxamic acids) sacrificial oxidants, relying on dual photoredox/hydrogen atom transfer (HAT) catalysis.
Language: Английский