Trauma Burden Affected People with Multiple Sclerosis During SARS-CoV-2 Pandemic

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(8), P. 2665 - 2665

Published: April 13, 2025

Background/Objectives: Trauma is a psychological injury resulting from distressing or overwhelming event. The SARS-CoV-2 pandemic has been disruptive and traumatic for many people with multiple sclerosis (pwMS). relationship between patient characteristics trauma in pwMS during the not yet thoroughly explored. aim of this bicentric prospective cohort study was to analyze prevalence development probable post-traumatic stress disorder (PTSD) among identify parameters associated condition. Methods: We have assessed PTSD before after approval first vaccines Germany using an adapted version Screening Questionnaire (TSQ). compared (TSQ sum score ≥ 6) those without < regarding sociodemographic MS-specific clinical characteristics, polypharmacy status, comorbidities, anxiety/depression levels, personality traits, mental/physical/social burden, general vaccination willingness. Results: Out 149 included, 8.1% were identified as having PTSD. These patients had significantly higher rates pre-pandemic abnormal anxiety (66.7% vs. 18.5%, p 0.001) depression scores (45.5% 12.6%, = 0.013). exhibited distinct profile, neuroticism harm avoidance lower conscientiousness, cooperativeness, self-directedness scores. They also more likely report severe very burdens (p ≤ 0.045). Conclusions: Medical social services should be provided support who experienced serious trauma. concepts education procedures accompanied by comprehensive clear communication that recognizes individual risk factors addresses possible concerns evidence-based convincing arguments.

Language: Английский

Vaccination status and self-reported side effects after SARS-CoV-2 vaccination in relation to psychological and clinical variables in patients with multiple sclerosis

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: May 28, 2024

Abstract The recent SARS-CoV-2 pandemic and the vaccination campaign posed a challenge to patients with autoimmune disease, such as multiple sclerosis (MS). We aimed for investigating whether psychological/sociodemographic/clinical characteristics of MS are associated status self-reported side effects (SEs). have asked about their willingness receive recommended standard vaccinations pre-pandemically since June 2019. Between 10/2021 01/2022, we surveyed 193 these current status, perception vaccination-related SEs, reasons against vaccination. 75.6% declared before pandemic. 84.5%, 78.2%, 13.0% had received first, second, third vaccination, respectively, until follow-up survey. most common reason not getting vaccinated was concern possible (82.1%), followed by belief that vaccines been adequately tested (64.3%). Vaccination-related SEs were reported 52.8% patients. Younger age, higher education, lower degree disability, relapsing disease course, shorter duration, receiving disease-modifying therapy anxiety depression levels occurrence certain SEs. Concerns novel widespread among necessitate targeted education patients, especially those more severe psychopathological symptoms (anxiety or depression) who generally skeptical

Language: Английский