Bulletin of the Chemical Society of Japan, Journal Year: 2024, Volume and Issue: 97(4)
Published: March 28, 2024
Abstract Electrochemical reduction of the trimethylsilyl enolates alkyl aryl ketones induces retro-Brook rearrangement to provide 1-aryl-1-trimethylsilylalkan-1-ols. The transformation proceeds through a sequence 1) single-electron silyl enolate, 2) protonation with phenol, 3) another form siloxy-substituted benzylic anion, and 4) pivotal rearrangement.
Language: Английский
Bulletin of the Chemical Society of Japan, Journal Year: 2024, Volume and Issue: 97(4)
Published: March 28, 2024
Abstract Electrochemical reduction of the trimethylsilyl enolates alkyl aryl ketones induces retro-Brook rearrangement to provide 1-aryl-1-trimethylsilylalkan-1-ols. The transformation proceeds through a sequence 1) single-electron silyl enolate, 2) protonation with phenol, 3) another form siloxy-substituted benzylic anion, and 4) pivotal rearrangement.
Language: Английский
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