Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2665 - 2665
Published: Dec. 22, 2024
The
increasing
prevalence
of
harmful
algal
blooms
(HABs)
driven
by
eutrophication,
particularly
in
China's
nearshore
waters,
is
a
growing
concern.
Dinoflagellate
Heterocapsa
bohaiensis
have
caused
significant
ecological
and
economic
damage,
as
well
mass
mortality,
cultivated
species.
Nutrients
are
one
the
primary
inducers
H.
blooms.
However,
transcriptomic
studies
remain
sparse,
its
metabolic
pathways
unknown.
This
study
analyzed
transcriptome
under
varying
nutrient
conditions
(nitrogen
at
128,
512,
880
μM;
phosphate
8,
6,
32
μM),
focusing
on
differential
gene
expression.
results
indicated
that
deviations
(higher
or
lower
N:P
ratios)
led
to
higher
number
differentially
expressed
genes
compared
control
(N:P
ratios
=
27.5),
thereby
underscoring
their
pivotal
role
growth.
Gene
Ontology
(GO)
enrichment
analyses
showed
limitation
upregulated
biosynthesis
catabolism
processes
while
downregulating
cell
cycle
division
functions.
Kyoto
Encyclopedia
Genes
Genomes
(KEGG)
analysis
revealed
that,
nitrogen
limitation,
proteasome
were
upregulated,
photosynthesis
carbon
fixation
downregulated;
phosphorus
metabolism
was
downregulated.
These
findings
suggest
adapts
stress
adjusting
processes.
Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(11), P. 494 - 494
Published: Nov. 1, 2024
The
pursuit
of
highly
effective,
low-toxicity,
and
eco-friendly
algicides
for
controlling
eradicating
harmful
algal
blooms
(HABs)
is
paramount
importance.
natural
allelochemical
bacillamide
A
has
displayed
impressive
algicidal
activity
against
algae
with
favorable
safety
profiles.
However,
the
poor
synthetic
efficiency
large
dose
requirements
limit
its
further
application.
In
this
paper,
17
thiazole-containing
derivatives
(BDs)
were
designed
synthesized
in
three
linear
steps
as
potential
algicides.
Eight
compounds
(
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2665 - 2665
Published: Dec. 22, 2024
The
increasing
prevalence
of
harmful
algal
blooms
(HABs)
driven
by
eutrophication,
particularly
in
China's
nearshore
waters,
is
a
growing
concern.
Dinoflagellate
Heterocapsa
bohaiensis
have
caused
significant
ecological
and
economic
damage,
as
well
mass
mortality,
cultivated
species.
Nutrients
are
one
the
primary
inducers
H.
blooms.
However,
transcriptomic
studies
remain
sparse,
its
metabolic
pathways
unknown.
This
study
analyzed
transcriptome
under
varying
nutrient
conditions
(nitrogen
at
128,
512,
880
μM;
phosphate
8,
6,
32
μM),
focusing
on
differential
gene
expression.
results
indicated
that
deviations
(higher
or
lower
N:P
ratios)
led
to
higher
number
differentially
expressed
genes
compared
control
(N:P
ratios
=
27.5),
thereby
underscoring
their
pivotal
role
growth.
Gene
Ontology
(GO)
enrichment
analyses
showed
limitation
upregulated
biosynthesis
catabolism
processes
while
downregulating
cell
cycle
division
functions.
Kyoto
Encyclopedia
Genes
Genomes
(KEGG)
analysis
revealed
that,
nitrogen
limitation,
proteasome
were
upregulated,
photosynthesis
carbon
fixation
downregulated;
phosphorus
metabolism
was
downregulated.
These
findings
suggest
adapts
stress
adjusting
processes.
