Highly Sensitive Biosensors Based on All-PEDOT:PSS Organic Electrochemical Transistors with Laser-Induced Micropatterning

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(35), P. 46664 - 46676

Published: Aug. 24, 2024

Recent advances in numerous biological applications have increased the accuracy of monitoring level biologically significant analytes human body to manage personal nutrition and physiological conditions. However, despite promising reports about costly wearable devices with high sensing performance, there has been a growing demand for inexpensive sensors that can quickly detect molecules. Herein, we present highly sensitive biosensors based on organic electrochemical transistors (OECTs), which are types semiconductor-based operate consistently at low operating voltages aqueous solutions. Instead gold or platinum electrode used current devices, poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) was as both channel gate electrodes OECT. Additionally, overcome patterning resolution limitations conventional solution processing, confirmed irradiation high-power IR laser (λ = 1064 nm) onto coated PEDOT:PSS film able produce spatially resolvable micropatterns digital-printing manner. The proposed technique exhibits suitability fabrication all-PEDOT:PSS OECT devices. device geometry optimized by fine-tuning area channel-to-gate distance. Consequently, sensor detecting ascorbic acid (vitamin C) concentrations an electrolyte exhibited best sensitivity 125 μA dec–1 limit detection 1.3 μM, is nearly 2 orders magnitude higher than previous findings. Subsequently, all-plastic flexible epidermal biosensor established transferring patterned from glass substrate PET substrate, taking full advantage flexibility PEDOT:PSS. prepared cost-effective suitable single-use because its acceptable performance reliable signal vitamin C. successfully obtained temporal profile C sweat volunteer after consumption drinks. We believe fabricated using accurate process versatile potential low-cost emerging bioelectronic applications.

Language: Английский

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Metal oxide-polymer composites for gas-sensing applications

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 107 - 150

Published: Jan. 1, 2024

Language: Английский

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Water-based direct photopatterning of stretchable PEDOT:PSS using amphiphilic block copolymers

npj Flexible Electronics, Journal Year: 2024, Volume and Issue: 8(1)

Published: April 3, 2024

Abstract The use of water-based chemistry in photolithography during semiconductor fabrication is desirable due to its cost-effectiveness and minimal environmental impact, especially considering the large scale production. Despite these benefits, limited research has reported successful demonstrations photopatterning, particularly for intrinsically water-soluble materials such as Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) significant challenges achieving selective dissolution developing process. In this paper, we propose a method direct patterning PEDOT:PSS water by introducing an amphiphilic Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (PEO-PPO-PEO, P123) block copolymer film. addition enhances stretchability composite film reduces hydrophilicity surface, allowing absorption only after UV exposure through photoinitiated reaction with benzophenone. We apply technique fabricate tactile wearable biosensors, both which benefit from mechanical transparency PEDOT:PSS. Our represents promising solution photopatterning hydrophilic materials, potential wider applications fabrication.

Language: Английский

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Recent progress on PEDOT‐based wearable bioelectronics

View, Journal Year: 2022, Volume and Issue: 3(5)

Published: Oct. 31, 2022

Abstract Bioelectronics, which can perform monitoring and biological signal collection of strain, pressure, temperature at the same time, have attracted more attentions. To meet unique requirements wearable characteristics, bioelectronic device with excellent flexibility is desired. At present, biggest challenge for flexible candidate electrode materials. The classical conducting polymer poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has showed a promising potential in field devices due to its high conductivity, flexibility, aqueous processability, good biocompatibility. Here, we reviewed recent progress PEDOT‐based sensors focus on role different materials addressing mechanical requirements. impact contemporary research will be highlighted.

Language: Английский

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A Biobattery Capsule for Ingestible Electronics in the Small Intestine: Biopower Production from Intestinal Fluids Activated Germination of Exoelectrogenic Bacterial Endospores

Advanced Energy Materials, Journal Year: 2022, Volume and Issue: 13(1)

Published: Nov. 28, 2022

Abstract Functioning ingestible capsules offer tremendous promise for a plethora of diagnostic and therapeutic applications. However, the absence realistic practical power solutions has greatly hindered development electronics. Microbial fuel cells (MFCs) hold great potential as sources such devices small intestinal environment maintains steady internal temperature neutral pH. Those conditions constant supply nutrient‐rich organics are perfect to generate long‐lasting power. Although previous small‐scale MFCs have demonstrated many promising applications, little is known about generating in human gut environment. Here, this work reports design operation microbial biobattery capsule Dormant Bacillus subtilis endospores storable anodic biocatalyst that will provide on‐demand when revived by fluids. A conductive, porous, poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate hydrogel anode enables superior electrical performance what world's smallest MFC. Moreover, an oxygen‐rich cathode its effective cathodic capability even oxygen‐deficit As proof‐of‐concept demonstration stimulated fluid, produces current density 470 µA cm −2 98 µW , ensuring efficacy novel sole source applications intestine.

Language: Английский

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