Linking wall shear stress and vorticity topologies: Toward a unified theory of cardiovascular flow disturbances

Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(6)

Published: June 1, 2024

Broadening current knowledge about the complex relationship at blood-vessel wall interface is a main challenge in hemodynamics research. Moving from consideration that shear stress (WSS) provides signature for near-wall velocity dynamics and vorticity considered skeleton of fluid motion, here we present unified theory demonstrating existing link between surface (SV) WSS topological skeletons, latter recently emerged as predictor vascular disease. The analysis focused on SV fixed points, i.e., points where fields vanish, they play major role shaping vector field features. theoretical proves that: (i) all must necessarily be although with differences nature stability (ii) point not point. In former case, are consequence flow patterns only contributes to vorticity; impingement to/emanation vessel wall. Moreover, structures interacting characterized by zero or non-zero rotational momentum generate different nature/stability. High-fidelity computational simulations intracranial aneurysm models confirmed applicability considerations. presented unambiguously explains mechanistic disturbances underlying intravascular features expressed terms vorticity, ultimately facilitating clearer interpretation local pathophysiology.

Language: Английский

A revised and expanded unified theory linking wall shear stress and vorticity topologies to enable the interpretation of cardiovascular flow disturbances

Physics of Fluids, Journal Year: 2025, Volume and Issue: 37(3)

Published: March 1, 2025

Deciphering the complex interactions at blood vessel–wall interface remains a key challenge in hemodynamics research. Wall shear stress (WSS) is recognized as signature for near-wall velocity dynamics, while vorticity represents fundamental structure of fluid motion. In this work, we revise and extend recently proposed unifying theoretical approach that sought to connect topological features surface (SV) WSS [Mazzi, Gallo, Calò, Steinman, Morbiducci, “Linking wall topologies: Toward unified theory cardiovascular flow disturbances,” Phys. Fluids 36(6), 61905 (2024)], latter gaining momentum predictor vascular disease. By revising partially erroneous interpretation link between SV fixed points (focal on luminal where these fields vanish), demonstrate here every point also point, vice versa, though their nature stability may differ. Building upon previous study, establish robust classification possible combinations points, based stability, mechanistically them structures. These structures can further be distinguished by presence or absence diffusion flux normal wall, depending local kinematics. High-resolution computational dynamics simulations intracranial aneurysm models validate insights. This framework offers clear taxonomy describing mechanistic relationship disturbances intravascular hemodynamics, providing deeper understanding how forces are influenced structures, paving way clearer role pathophysiology.

Language: Английский

Identification of vortex boundaries in two-dimensional incompressible flows based on the Liutex-shear interaction

Journal of Hydrodynamics, Journal Year: 2023, Volume and Issue: 35(5), P. 825 - 831

Published: Oct. 1, 2023

Language: Английский