Design, construction and validation of a magnetic particle imaging (MPI) system for human brain imaging DOI Creative Commons
Eli Mattingly, Monika Śliwiak, Erica E. Mason

et al.

Physics in Medicine and Biology, Journal Year: 2024, Volume and Issue: 70(1), P. 015019 - 015019

Published: Dec. 11, 2024

Magnetic particle imaging (MPI) was introduced in 2005 as a promising, tracer-based medical modality with the potential for high sensitivity and spatial resolution. Since then, numerous preclinical devices have been built but only few human-scale devices, none of which targeted functional neuroimaging. In this work, we probe challenges scaling technology to meet needs human neuroimaging sufficient detecting hemodynamic changes following brain activation spatio-temporal resolution comparable current magnetic resonance approaches.

Language: Английский

Design and Optimization of a Magnetic Field Generator for Magnetic Particle Imaging with Soft Magnetic Materials DOI Creative Commons
Fynn Foerger, Marija Boberg, Jonas Faltinath

et al.

Advanced Intelligent Systems, Journal Year: 2024, Volume and Issue: 6(11)

Published: Aug. 22, 2024

Magnetic field generators are a key component of Particle Imaging (MPI) systems, and their power consumption is major obstacle on the path to human‐sized scanners. Despite importance, focused discussion these rare, comprehensive description design process currently lacking. This work presents methodology for optimization selection operating with soft magnetic materials outside linear regime in context MPI. Key elements mathematical model generators, formalism defining sequences, relationship between sequence. These used define space generator given its system requirements constraints. The then formulated as an problem. Subsequently, this utilized new specifically cerebral imaging studies. result outperforms our existing MPI terms view size, providing proof‐of‐concept entire methodology. As approach very general, it can be extended beyond other areas such manipulation medical devices micro‐robotics.

Language: Английский

Citations

1

Design, construction and validation of a magnetic particle imaging (MPI) system for human brain imaging DOI Creative Commons
Eli Mattingly, Monika Śliwiak, Erica E. Mason

et al.

Physics in Medicine and Biology, Journal Year: 2024, Volume and Issue: 70(1), P. 015019 - 015019

Published: Dec. 11, 2024

Magnetic particle imaging (MPI) was introduced in 2005 as a promising, tracer-based medical modality with the potential for high sensitivity and spatial resolution. Since then, numerous preclinical devices have been built but only few human-scale devices, none of which targeted functional neuroimaging. In this work, we probe challenges scaling technology to meet needs human neuroimaging sufficient detecting hemodynamic changes following brain activation spatio-temporal resolution comparable current magnetic resonance approaches.

Language: Английский

Citations

1