Recent advances and applications of artificial intelligence in 3D bioprinting

Biophysics Reviews, Journal Year: 2024, Volume and Issue: 5(3)

Published: July 19, 2024

3D bioprinting techniques enable the precise deposition of living cells, biomaterials, and biomolecules, emerging as a promising approach for engineering functional tissues organs. Meanwhile, recent advances in researchers to build vitro models with finely controlled complex micro-architecture drug screening disease modeling. Recently, artificial intelligence (AI) has been applied different stages bioprinting, including medical image reconstruction, bioink selection, printing process, both classical AI machine learning approaches. The ability handle datasets, make computations, learn from past experiences, optimize processes dynamically makes it an invaluable tool advancing bioprinting. review highlights current integration discusses future approaches harness synergistic capabilities developing personalized

Language: Английский

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Hybrid 3D microfluidic bioprinting for the engineering of cancer models and tissue substitutes

Virtual and Physical Prototyping, Journal Year: 2024, Volume and Issue: 19(1)

Published: Nov. 4, 2024

3D bioprinting is at the forefront of tissue engineering to fabricate complex constructs resembling functional tissues. However, inability produce heterogeneous tissues and lack spatio-temporal control over release bioactive factors are greatly limiting clinical translation. Herein, combination with high-throughput dispensing using a custom microfluidic system nanoclay-based inks presented. This approach was found enhance printability, retention, controlled factors. Advanced models were developed resemble cancer skeletal tissue, while studying effect anti-cancer (Doxorubicin) pro-osteogenic growth (bone morphogenetic protein-2, BMP-2), respectively. The new nanoclay ink allowed sustained release, making it suitable for long-term applications. These findings suggest that by combining delivery platform can be assembled, offering significant advancements in regenerative medicine.

Language: Английский

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Size-dependent penetration depth of colloidal nanoparticles into cell spheroids

Advanced Drug Delivery Reviews, Journal Year: 2025, Volume and Issue: 222, P. 115593 - 115593

Published: May 6, 2025

Language: Английский

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Assembly of a tumor microtissue by stacking normal and cancer spheroids on Kenzan using a bio-3D printer to monitor dynamic cancer cell invasion in the microtissue

Biochemical Engineering Journal, Journal Year: 2024, Volume and Issue: 212, P. 109536 - 109536

Published: Oct. 19, 2024

Language: Английский

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