Male animal sterilization: history, current practices, and potential methods for replacing castration

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: July 3, 2024

Sterilization and castration have been synonyms for thousands of years. Making an animal sterile meant to render them incapable producing offspring. Castration or the physical removal testes was discovered be most simple but reliable method managing reproduction sexual behavior in male. Today, there continues global utilization domestic animals. More than six hundred million pigs are castrated every year, surgical dogs cats is a routine practice veterinary medicine. However, modern biological research has extended meaning sterilization include methods that spare testis involve variety options, from chemical immunocastration various vasectomy. This review begins with history sterilization, showing direct link between its man Then, it traces evolution concepts inducing sterility, where overlapped basic studies reproductive hormones discovery testicular toxicants, some which serve as sterilizing agents rodent pests. Finally, recent efforts use immune system gene editing block hormonal stimulation function discussed. As we respond crisis overpopulation strive better welfare, these novel provide optimism replacing species.

Language: Английский

Effects of Immunocastration and Amino Acid Supplementation on Yearling Fallow Deer (Dama dama) Testes Development

Animals, Journal Year: 2023, Volume and Issue: 14(1), P. 115 - 115

Published: Dec. 28, 2023

Forty-four fallow deer bucks (10 months old; 22.9 ± 2.4 kg) were utilized to investigate the effects of immunocastration and amino acid supplementation on testes development. Immunocastrated administered Improvac® at weeks 1, 8, 20 this study (control group: intact males). Starting week half each sex received rumen-protected lysine methionine (3:1) supplementation. At slaughter (week 37/39), body size, internal fat deposits, antler size parameters, weight, surface color, cauda epididymal sperm viability morphology, seminiferous tubule circumference epithelium thickness determined. Animals with larger sizes, greater forequarter development, growth also had Whilst result is unexpected, tissue showed impaired development (atrophied tubules), decreased viability, normal morphology. Testes from immunocastrated was less red, possibly indicating reduced blood supply. Conversely, increased testes’ redness males fed acids greatest Thus, may be a welfare-friendly alternative for venison production. results support findings literature that not reliable indicator success, warrants further investigation in over different physiological stages.

Language: Английский