Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks

Nature Medicine, Journal Year: 2020, Volume and Issue: 26(1), P. 52 - 58

Published: Jan. 1, 2020

Language: Английский

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Mechanisms of immunotherapy resistance: lessons from glioblastoma

Nature Immunology, Journal Year: 2019, Volume and Issue: 20(9), P. 1100 - 1109

Published: July 29, 2019

Language: Английский

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Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

Nature reviews. Cancer, Journal Year: 2014, Volume and Issue: 14(2), P. 92 - 107

Published: Jan. 24, 2014

Language: Английский

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An anatomic transcriptional atlas of human glioblastoma

Science, Journal Year: 2018, Volume and Issue: 360(6389), P. 660 - 663

Published: May 10, 2018

Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor's molecular and cellular landscapes are complex, their relationships to histologic features routinely used for diagnosis unclear. We present the Ivy Atlas, anatomically based transcriptional atlas of human glioblastoma aligns individual with genomic alterations gene expression patterns, thus assigning information most important morphologic hallmarks tumor. its clinical database freely accessible online data resources will serve as valuable platform future investigations pathogenesis, diagnosis, treatment.

Language: Английский

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A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

Nature, Journal Year: 2015, Volume and Issue: 525(7568), P. 261 - 264

Published: Aug. 24, 2015

Language: Английский

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