The role of microbiota in the pathophysiology of uterine fibroids – a systematic review DOI Creative Commons

Lidia Korczynska,

Natalia Żeber‐Lubecka, Magdalena Zgliczyńska

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2023, Volume and Issue: 13

Published: May 26, 2023

For a long time, the uterus had been considered sterile organ, meaning that under physiological conditions would not be colonized by bacteria. Based on available data, it may concluded gut and uterine microbiome are related, role of this is greater than expected. Despite being most common pelvic neoplasms in women reproductive age, fibroids (UFs) still poorly understood tumors whose etiology has fully determined. This systematic review presents relationship between intestinal dysbiosis fibroids. A three medical databases was carried out: MEDLINE/PubMed, Scopus Cochrane. In study, 195 titles abstracts were reviewed, including only original articles clinical trials criteria. Finally, 16 studies included to analysis. recent years, researchers dealing with reproduction broad sense have focused various locations study its pathogenesis and, consequently, prevention treatment diseases genital organ. Conventional microbial detection methods suitable for identifying bacteria, which difficult culture. Next-generation sequencing (NGS) provides an easier faster more informative analysis bacterial populations. It seems microbiota potential risk factor or affect disease process. Some changes shown many types such as Firmicutes, Proteobacteria, Actinobacteria Verrucomicrobia detected fecal samples patients view few results link fibroids, further intensive humans animal models necessary, possible use different modulations

Language: Английский

Fate of progesterone and norgestrel in anaerobic/anoxic/oxic (A/A/O) process: Insights from biotransformation and mass flow DOI

Xianda Hu,

Jinju Geng, Fuzheng Zhao

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 856, P. 158844 - 158844

Published: Sept. 17, 2022

Language: Английский

Citations

12

Characterization and low-temperature biodegradation mechanism of 17β-estradiol-degrading bacterial strain Rhodococcus sp. RCBS9 DOI
Peng Hao,

Zongshuo Lv,

Hanyu Pan

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 240, P. 117513 - 117513

Published: Oct. 27, 2023

Language: Английский

Citations

7

Suitability of Immobilized Systems for Microbiological Degradation of Endocrine Disrupting Compounds DOI Creative Commons
Danuta Wojcieszyńska, Ariel Marchlewicz, Urszula Guzik

et al.

Molecules, Journal Year: 2020, Volume and Issue: 25(19), P. 4473 - 4473

Published: Sept. 29, 2020

The rising pollution of the environment with endocrine disrupting compounds has increased interest in searching for new, effective bioremediation methods. Particular attention is paid to search microorganisms high degradation potential and possibility their use compounds. Increasingly, immobilized or enzymes are used biodegradation systems. This review presents main sources identifies risks associated presence environment. pathways these by also presented. last part devoted an overview immobilization methods purposes enabling biocatalysts environmental bioremediation.

Language: Английский

Citations

18

Biocatalytic One-Carbon Transfer – A Review DOI
Michael Müller, Philipp Germer, Jennifer N. Andexer

et al.

Synthesis, Journal Year: 2022, Volume and Issue: 54(20), P. 4401 - 4425

Published: Aug. 8, 2022

Abstract This review provides an overview of different C1 building blocks as substrates enzymes, or part their cofactors, and the resulting­ functionalized products. There is emphasis on broad range possibilities biocatalytic one-carbon extensions with sources oxidation states. The identification uncommon biosynthetic strategies, many which might serve templates for synthetic biotechnological applications, towards supported by recent genomic metabolomic progress hence we refer principally to literature spanning from 2014 2020. 1 Introduction 2 Methane, Methanol, Methylamine 3 Glycine 4 Nitromethane 5 SAM Ylide 6 Other Building Blocks 7 Formaldehyde Glyoxylate Equivalents 8 Cyanide 9 Formic Acid 10 Formyl-CoA Oxalyl-CoA 11 Carbon Monoxide 12 Dioxide 13 Conclusions

Language: Английский

Citations

11

The role of microbiota in the pathophysiology of uterine fibroids – a systematic review DOI Creative Commons

Lidia Korczynska,

Natalia Żeber‐Lubecka, Magdalena Zgliczyńska

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2023, Volume and Issue: 13

Published: May 26, 2023

For a long time, the uterus had been considered sterile organ, meaning that under physiological conditions would not be colonized by bacteria. Based on available data, it may concluded gut and uterine microbiome are related, role of this is greater than expected. Despite being most common pelvic neoplasms in women reproductive age, fibroids (UFs) still poorly understood tumors whose etiology has fully determined. This systematic review presents relationship between intestinal dysbiosis fibroids. A three medical databases was carried out: MEDLINE/PubMed, Scopus Cochrane. In study, 195 titles abstracts were reviewed, including only original articles clinical trials criteria. Finally, 16 studies included to analysis. recent years, researchers dealing with reproduction broad sense have focused various locations study its pathogenesis and, consequently, prevention treatment diseases genital organ. Conventional microbial detection methods suitable for identifying bacteria, which difficult culture. Next-generation sequencing (NGS) provides an easier faster more informative analysis bacterial populations. It seems microbiota potential risk factor or affect disease process. Some changes shown many types such as Firmicutes, Proteobacteria, Actinobacteria Verrucomicrobia detected fecal samples patients view few results link fibroids, further intensive humans animal models necessary, possible use different modulations

Language: Английский

Citations

5