To what extent do physiological tolerances determine elevational range limits of mammals? DOI Creative Commons
Jay F. Storz, Graham R. Scott

The Journal of Physiology, Journal Year: 2023, Volume and Issue: 602(21), P. 5475 - 5484

Published: Oct. 27, 2023

Abstract A key question in biology concerns the extent to which distributional range limits of species are determined by intrinsic physiological tolerance. Here, we use common‐garden data for wild rodents assess whether with higher elevational typically have thermogenic capacities comparison closely related lowland species. Among South American leaf‐eared mice (genus Phyllotis ), mean performance is limits, but there little among‐species variation magnitude plasticity this trait. In North rodent genus Peromyscus , highland deer ( maniculatus ) greater maximal oxygen uptake () than white‐footed leucopus at a level hypoxia that matches upper limit former mice, enhanced attributable combination evolved and plastic changes pathways govern transport utilization O 2 metabolic substrates. Experiments also demonstrate exposure during different stages development elicits cardiorespiratory traits improve via distinct mechanisms. Evolved differences capacity provide clues about why some able persist higher‐elevation habitats lie slightly beyond tolerable other Such environmental tolerance suggest might be more vulnerable climate change others. image

Language: Английский

Raman-guided exploration of placental microplastic exposure: Unraveling the polymeric tapestry and assessing developmental implications DOI
Yun Xiang, Liyang Liang, Jiaqi Tian

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 477, P. 135271 - 135271

Published: July 20, 2024

Language: Английский

Citations

6

Evolution of Litter Size: Proximate and Ultimate Mechanisms DOI Creative Commons
Kathryn Wilsterman,

Anna Isabel Bautista,

Chloe E. Butler

et al.

Integrative and Comparative Biology, Journal Year: 2024, Volume and Issue: unknown

Published: May 26, 2024

Relative reproductive success and failure are the ultimate determinants of Darwinian fitness. As such, traits variation therein have an immediate considerable impact on evolutionary trajectory lineages. Historically, significant attention has been paid to ecological processes (ultimate factors) that shape diversity canalization within groups better our understanding organismal population or species resilience. In contrast, physiological systems mediate among (i.e., proximate in remain a black box. To-date, there is comparatively little information about how mechanisms constrain promote potential traits. this mini-review, we focus litter size Eutherian mammals as trait with relatively well-defined (litter sizes well-described both across species) for which some genetic identified. We discuss special breadth may act "toggle" switches evolution size. close brief discussion role plasticity play lay out several forward-looking areas future research.

Language: Английский

Citations

1

Placental–Heart Axis: An Evolutionary Perspective DOI Open Access
J. Matthews,

B. Rajakumar,

Chrystalle Katte Carreon

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(20), P. 11212 - 11212

Published: Oct. 18, 2024

To maintain its development, the growing fetus is directly dependent on placenta, an organ that acts as both a modulator and mediator. As essential component of pregnancy derived from maternal fetal tissues, placenta facilitates passage all oxygen nutrients expecting parent to their fetuses. Further, conveys multiple impacts environment fetus. The timing placental development parallels cardiovascular system, anomalies are implicated potential cause congenital heart disease. For example, disease more common in pregnancies complicated by preeclampsia, condition characterized dysfunction. Given placenta’s intermediary links health outcomes, it emerging focus evolutionary medicine, which seeks understand how interactions between humans affect our biology give rise present review provides overview developmental courses well implications infant health.

Language: Английский

Citations

1

United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals DOI Open Access
Hagar K Soliman,

Jenn M. Coughlan

Journal of Heredity, Journal Year: 2024, Volume and Issue: 115(6), P. 625 - 642

Published: Feb. 16, 2024

Abstract Endosperm in angiosperms and placenta eutherians are convergent innovations for efficient embryonic nutrient transfer. Despite advantages, this reproductive strategy incurs metabolic costs that maternal parents disproportionately shoulder, leading to potential inter-parental conflict over optimal offspring investment. Genomic imprinting—parent-of-origin-biased gene expression—is fundamental endosperm development has convergently evolved mammals, part, resolve parental conflict. Here, we review the mechanisms of genomic imprinting these taxa. differences timing spatial extent imprinting, taxa exhibit remarkable convergence molecular machinery genes governing imprinting. We then assess role shaping evolution within using four criteria: 1) Do sibling relatedness cause inferred strength conflict? 2) reciprocal crosses between with different histories parent-of-origin growth effects? 3) Are effects caused by dosage-sensitive do loci signals positive selection? 4) Can normal be restored perturbations restore stoichiometric balance endosperm/placenta? Although find evidence all criteria eutherians, suggesting may help shape their evolution, many questions remain. Additionally, myriad two suggest respective biologies how/when/where/to what manifests. Lastly, discuss outstanding questions, highlighting power comparative work quantifying evolution.

Language: Английский

Citations

1

To what extent do physiological tolerances determine elevational range limits of mammals? DOI Creative Commons
Jay F. Storz, Graham R. Scott

The Journal of Physiology, Journal Year: 2023, Volume and Issue: 602(21), P. 5475 - 5484

Published: Oct. 27, 2023

Abstract A key question in biology concerns the extent to which distributional range limits of species are determined by intrinsic physiological tolerance. Here, we use common‐garden data for wild rodents assess whether with higher elevational typically have thermogenic capacities comparison closely related lowland species. Among South American leaf‐eared mice (genus Phyllotis ), mean performance is limits, but there little among‐species variation magnitude plasticity this trait. In North rodent genus Peromyscus , highland deer ( maniculatus ) greater maximal oxygen uptake () than white‐footed leucopus at a level hypoxia that matches upper limit former mice, enhanced attributable combination evolved and plastic changes pathways govern transport utilization O 2 metabolic substrates. Experiments also demonstrate exposure during different stages development elicits cardiorespiratory traits improve via distinct mechanisms. Evolved differences capacity provide clues about why some able persist higher‐elevation habitats lie slightly beyond tolerable other Such environmental tolerance suggest might be more vulnerable climate change others. image

Language: Английский

Citations

2