Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors DOI Creative Commons
Runhan Liu, Jiaxin Zhou, Xiaochen Chen

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 13(1), P. 47 - 47

Published: Dec. 28, 2024

Gastrointestinal tumors present a significant challenge for precision medicine due to their complexity, necessitating the development of more specific diagnostic tools and therapeutic agents. Recent advances have positioned coding non-coding RNAs as emerging biomarkers these malignancies, detectable by liquid biopsies, innovative Many RNA-based therapeutics, such small interfering RNA (siRNA) antisense oligonucleotides (ASO), entered clinical trials or are available on market. This review provides narrative examination potential in gastrointestinal cancers, with an emphasis its application medicine. discusses current challenges, drug resistance tumor metastasis, highlights how molecules can be leveraged targeted detection treatment. Additionally, this categorizes targets based tissue type, offering comprehensive analysis role advancing tumors.

Language: Английский

Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors DOI Creative Commons
Runhan Liu, Jiaxin Zhou, Xiaochen Chen

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 13(1), P. 47 - 47

Published: Dec. 28, 2024

Gastrointestinal tumors present a significant challenge for precision medicine due to their complexity, necessitating the development of more specific diagnostic tools and therapeutic agents. Recent advances have positioned coding non-coding RNAs as emerging biomarkers these malignancies, detectable by liquid biopsies, innovative Many RNA-based therapeutics, such small interfering RNA (siRNA) antisense oligonucleotides (ASO), entered clinical trials or are available on market. This review provides narrative examination potential in gastrointestinal cancers, with an emphasis its application medicine. discusses current challenges, drug resistance tumor metastasis, highlights how molecules can be leveraged targeted detection treatment. Additionally, this categorizes targets based tissue type, offering comprehensive analysis role advancing tumors.

Language: Английский

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