Short-term fluctuating and long-term divergent selection on sympatric Monkeyflowers: insights from decade-spanning reciprocal transplants DOI Creative Commons
Caroline M. Dong, Bolívar Aponte Rolón,

Juj K. Sullivan

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 29, 2024

ABSTRACT Sympatric species are often locally adapted to distinct microhabitats. However, temporal variation may cause local maladaptation and boundary breakdown, especially during extreme climatic events leading episodic selection. Repeated reciprocal transplants can reveal the interplay between short long-term patterns of natural To examine evolutionary trajectories sympatric Monkeyflowers different niches, Mimulus guttatus M. laciniatus, we performed three replicated combined them with previous experiments leverage a dataset five spanning 10 years. We phenotypic selection analyses on parents hybrids in parental habitats Yosemite NP, CA years drastically differing snowpack. If there is ecological isolation, then predicted divergent line species’ differences adaptation. found interannual fluctuations selection, unpredicted directions. combined-year analysis detected longer-term flowering time, key temporally isolating adaptative trait, suggesting that reinforce boundaries despite short-term fluctuations. Finally, adaptation laciniatus low snowpack years, while an extremely high year contributed average .

Language: Английский

Neandertal ancestry through time: Insights from genomes of ancient and present-day humans DOI Creative Commons
Leonardo Nicola Martin Iasi, Manjusha Chintalapati, Laurits Skov

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: May 13, 2024

Abstract Gene flow from Neandertals has shaped the landscape of genetic and phenotypic variation in modern humans. We identify location size introgressed Neandertal ancestry segments more than 300 genomes spanning last 50,000 years. study how is shared among individuals to infer time duration gene flow. find correlation segment locations across their divergence sequenced Neandertals, both support a model single major Our catalog through confirms that most natural selection–positive negative–on variants occurred immediately after flow, provides new insights into contact with human origins adaptation.

Language: Английский

Citations

10
Swordtail fish hybrids reveal that genome evolution is surprisingly predictable after initial hybridization DOI Creative Commons
Quinn K. Langdon, Jeffrey S. Groh, Stepfanie M. Aguillon

et al.

PLoS Biology, Journal Year: 2024, Volume and Issue: 22(8), P. e3002742 - e3002742

Published: Aug. 26, 2024

Over the past 2 decades, biologists have come to appreciate that hybridization, or genetic exchange between distinct lineages, is remarkably common-not just in particular lineages but taxonomic groups across tree of life. As a result, genomes many modern species harbor regions inherited from related species. This observation has raised fundamental questions about degree which genomic outcomes hybridization are repeatable and natural selection drives such repeatability. However, lack appropriate systems answer these limited empirical progress this area. Here, we leverage independently formed hybrid populations swordtail fish Xiphophorus birchmanni X. cortezi address question. We find local ancestry one population predictive another, demographically independent population. Applying newly developed methods, can attribute much repeatability strong earliest generations after initial hybridization. complement analyses with time-series data demonstrates at under remained stable over approximately 40 evolution. Finally, compare our results well-studied × malinche conclude deeper evolutionary divergence resulted stronger higher patterns hybrids cortezi.

Language: Английский

Citations

6
Secondary Contact, Introgressive Hybridization, and Genome Stabilization in Sticklebacks DOI Creative Commons
Xueyun Feng, Juha Merilä, Ari Löytynoja

et al.

Molecular Biology and Evolution, Journal Year: 2024, Volume and Issue: 41(2)

Published: Feb. 1, 2024

Advances in genomic studies have revealed that hybridization nature is pervasive and raised questions about the dynamics of different genetic evolutionary factors following initial event. While recent research has proposed outcomes might be predictable to some extent, many uncertainties remain. With comprehensive whole-genome sequence data, we investigated introgression between 2 divergent lineages 9-spined sticklebacks (Pungitius pungitius) Baltic Sea. We found intensity direction selection on introgressed variation varied across elements: while functionally important regions displayed reduced rates introgression, promoter showed enrichment. Despite general trend negative selection, identified specific were enriched for variants, within these regions, detected footprints indicating adaptive introgression. Geographically, against functional changes strongest vicinity secondary contact zone weaken as a function distance from contact. Altogether, results suggest stabilization genomes complex, multistage process involving both positive selection. In spite predominance also evidence variants likely associated with adaptation Sea environmental conditions.

Language: Английский

Citations

5
Emergence of fungal hybrids – potential threat to humans. DOI
Jayaprakash Sasikumar,

Heena Azhar Shaikh,

Bharati Naik

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: unknown, P. 107278 - 107278

Published: Jan. 1, 2025

Language: Английский

Citations

0
Comparative analysis of multiple hybrid zones of Rhododendron × duclouxii uncovered different potential evolutionary outcomes DOI Creative Commons

Wei Zheng,

Li‐Jun Yan, Kevin S. Burgess

et al.

Plant Diversity, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans DOI
Leonardo Nicola Martin Iasi, Manjusha Chintalapati, Laurits Skov

et al.

Science, Journal Year: 2024, Volume and Issue: 386(6727)

Published: Dec. 12, 2024

Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments more than 300 genomes spanning the past 50,000 years. examined how is shared among individuals over time. Our analysis revealed that vast majority gene attributable to single, extended period occurred between 50,500 43,500 years ago, as evidenced by correlation, colocalization across individuals, divergence sequenced Neanderthals. Most natural selection-positive negative-on variants rapidly after flow. findings provide new insights into contact with human origins adaptation.

Language: Английский

Citations

3
Genome evolution is surprisingly predictable after initial hybridization DOI Creative Commons
Quinn K. Langdon, Jeffrey S. Groh, Stepfanie M. Aguillon

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 23, 2023

Over the past two decades, evolutionary biologists have come to appreciate that hybridization, or genetic exchange between distinct lineages, is remarkably common - not just in particular lineages but taxonomic groups across tree of life. As a result, genomes many modern species harbor regions inherited from related species. This observation has raised fundamental questions about degree which genomic outcomes hybridization are repeatable and natural selection drives such repeatability. However, lack appropriate systems answer these limited empirical progress this area. Here, we leverage independently formed hybrid populations swordtail fish

Language: Английский

Citations

7
Estimating scale-specific and localized spatial patterns in allele frequency DOI
Jesse R. Lasky, Margarita Takou, Diana Gamba

et al.

Genetics, Journal Year: 2024, Volume and Issue: 227(3)

Published: May 17, 2024

Abstract Characterizing spatial patterns in allele frequencies is fundamental to evolutionary biology because these contain evidence of underlying processes. However, the scales at which gene flow, changing selection, and drift act are often unknown. Many processes can operate inconsistently across space, causing nonstationary patterns. We present a wavelet approach characterize pattern frequency that helps solve problems. show how our relatedness multiple scales, i.e. multilocus genetic dissimilarity. also develop tests differentiation quantitative trait loci (QTL). With simulation, we illustrate methods under different scenarios. apply natural populations Arabidopsis thaliana population structure identify locally adapted scales. find, for example, flowering time QTL significantly elevated 300–1,300 km Wavelet transforms offer flexible way reveal geographic

Language: Английский

Citations

2
Gelada genomes highlight events of gene flow, hybridisation and local adaptation that track past climatic changes DOI Creative Commons
Matteo Caldon, Giacomo Mutti, Alessandro Mondanaro

et al.

Molecular Ecology, Journal Year: 2024, Volume and Issue: 33(19)

Published: Aug. 29, 2024

Abstract Theropithecus gelada , the last surviving species of this genus, occupy a unique and highly specialised ecological niche in Ethiopian highlands. A subdivision into three geographically defined populations (Northern, Central Southern) has been tentatively proposed for on basis genetic analyses, but genomic data have investigated only two these groups (Northern Central). Here we combined newly generated whole genome sequences individuals sampled from population living south East Africa Great Rift Valley with available other to reconstruct evolutionary history species. Integrating paleoclimatic found that gene‐flow across Papio tracked past climate changes. The isolation climatic conditions experienced by Southern geladas during Holocene shaped local diversity diet‐related signatures.

Language: Английский

Citations

1
Short-term fluctuating and long-term divergent selection on sympatric Monkeyflowers: insights from decade-spanning reciprocal transplants DOI Creative Commons
Caroline M. Dong, Bolívar Aponte Rolón,

Juj K. Sullivan

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 29, 2024

ABSTRACT Sympatric species are often locally adapted to distinct microhabitats. However, temporal variation may cause local maladaptation and boundary breakdown, especially during extreme climatic events leading episodic selection. Repeated reciprocal transplants can reveal the interplay between short long-term patterns of natural To examine evolutionary trajectories sympatric Monkeyflowers different niches, Mimulus guttatus M. laciniatus, we performed three replicated combined them with previous experiments leverage a dataset five spanning 10 years. We phenotypic selection analyses on parents hybrids in parental habitats Yosemite NP, CA years drastically differing snowpack. If there is ecological isolation, then predicted divergent line species’ differences adaptation. found interannual fluctuations selection, unpredicted directions. combined-year analysis detected longer-term flowering time, key temporally isolating adaptative trait, suggesting that reinforce boundaries despite short-term fluctuations. Finally, adaptation laciniatus low snowpack years, while an extremely high year contributed average .

Language: Английский

Citations

0