Shannon Holes, Black Holes and Knowledge: Can a Machine become a “Self-Aware" Teammate? DOI Open Access

William Lawless ---,

And Ira S. Moskowitz

Published: Feb. 19, 2024

We develop new theory from a broad case-study approach to explore better understanding of what constitutes knowledge and its value as identifiable human-machine teams. From past research, this trail exploration will lead these initial questions: What is the debate in furtherance knowledge? Will machines with AI be able contribute if we humans cannot define it or determine sufficiently for machine’s understanding, contribution, identification? Like humans, teammates, must usable that contributes team’s success field (e.g., testing "knowledge" field, identifying knowledge, using innovation) failure (viz., trouble shooting; weaknesses; discovering vulnerabilities, hiding by deception). It matters not whether public, private unexpressed an individual human machine agent alone; speculate process advances science autonomous teams assists interpretable learning. conclude questions speculation: How does become aware express awareness Can expressive teammates? And how teammate teammates possess sufficient perform task? structure “knowledge," once found, resistant alternatives (i.e., ordered); functional utility generalizable; applications are multifaceted (akin maximum entropy production). The complexity team taken into consideration our search which can also used information metric.

Language: Английский

Molecular assembly indices of mineral heteropolyanions: some abiotic molecules are as complex as large biomolecules DOI Creative Commons
Robert M. Hazen, Peter C. Burns, Henderson James Cleaves

et al.

Journal of The Royal Society Interface, Journal Year: 2024, Volume and Issue: 21(211)

Published: Feb. 1, 2024

Molecular assembly indices, which measure the number of unique sequential steps theoretically required to construct a three-dimensional molecule from its constituent atomic bonds, have been proposed as potential biosignatures. A central hypothesis theory is that any with an index ≥15 found in significant local concentrations represents unambiguous sign life. We show abiotic molecule-like heteropolyanions, assemble aqueous solution precursors some mineral crystals, range molecular indices 2 for H

Language: Английский

Citations

11
Assessing rural revitalization potential through rural transformation degree and sustainability: A quantitative study of 460 case villages in Lingbao, China DOI
Qianxi Zhang, Zhi Cao, Yansui Liu

et al.

Habitat International, Journal Year: 2024, Volume and Issue: 153, P. 103194 - 103194

Published: Oct. 5, 2024

Language: Английский

Citations

10
Assembly Theory: What It Does and What It Does Not Do DOI Creative Commons
Johannes Jaeger

Journal of Molecular Evolution, Journal Year: 2024, Volume and Issue: 92(2), P. 87 - 92

Published: March 7, 2024

A recent publication in Nature has generated much heated discussion about evolution, its tendency towards increasing diversity and complexity, potential status above beyond the known laws of fundamental physics. The argument at heart this controversy concerns assembly theory, a method to detect quantify influence higher-level emergent causal constraints computational worlds made basic objects their combinations. In short essay, I briefly review principles applications. then go on critically examine authors' assertions, concluding that theory merit but is not nearly as novel or revolutionary claimed. It certainly does provide any new explanation biological evolution natural selection, grounding biology regard, presentation paper starkly distorted by hype, which may explain some outrage it created.

Language: Английский

Citations

9
Minimally monophyletic genera are the cast-iron building blocks of evolution DOI Creative Commons
Richard H. Zander

Ukrainian Botanical Journal, Journal Year: 2024, Volume and Issue: 81(2), P. 87 - 99

Published: April 24, 2024

Detailed evaluation is provided for the statistical methods intrinsic to interlocking Sequential Bayes analysis, which allows estimation of evidential support stem-taxon dendrograms charting macroevolution taxa. It involves complexity functions, such as fractal evolution, generate well-supported evolutionary trees. Required are data on trait changes from ancestral species descendant species, facilitated by reduction large genera smallest included monophyletic groups (one inferred each). The genus here defined unit, turns out be monothetic at least direct species. key fact that most-recently acquired traits single apparently selectively inviolate and passed without change each immediate details sequential Bayesian analysis were clarified comparing optimal model with summed alternative models. Because confined arrangements only branches conjugate priors found operate all models simply one minus probability model. Such demonstrated optimum arrangement ancestor leads high values fitting theory, comparable levels reported molecular trees, may assumed similar model-building. method simple, free special computer well-suited standard taxonomic practice.

Language: Английский

Citations

7
Measuring Molecular Complexity DOI Creative Commons
Louie Slocombe, Sara Imari Walker

ACS Central Science, Journal Year: 2024, Volume and Issue: 10(5), P. 949 - 952

Published: May 8, 2024

ADVERTISEMENT RETURN TO ARTICLES ASAPPREVFirst ReactionsNEXTMeasuring Molecular ComplexityLeroy Cronin and his team showcase experiments to measure molecular complexity using spectroscopic techniques, applicable in drug discovery, characterizing molecule evolution, life detection.Louie SlocombeLouie SlocombeBeyond Center for Fundamental Concepts Science, Arizona State University, Tempe, 85287-0506, United StatesMore by Louie Slocombe Sara Imari Walker​Sara WalkerSchool of Earth Space Exploration, 85287-1004, StatesSchool StatesSanta Fe Institute, Santa Fe, New Mexico 87501, StatesEmail: [email protected]More WalkerCite this: ACS Cent. Sci. 2024, XXXX, XXX, XXX-XXXPublication Date (Web):May 8, 2024Publication History Published online8 May 2024https://doi.org/10.1021/acscentsci.4c00697Published 2024 American Chemical Society. This publication is licensed under CC-BY 4.0. License Summary*You are free share (copy redistribute) this article any medium or format adapt (remix, transform, build upon) the material purpose, even commercially within parameters below:Creative Commons (CC): a Creative license.Attribution (BY): Credit must be given creator.View full license*DisclaimerThis summary highlights only some key features terms actual license. It not license has no legal value. Carefully review before these materials. Open Access indicated. Learn MoreArticle Views-Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views COUNTER-compliant sum text downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated reflect usage leading up last few days.Citations number other articles citing article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score quantitative attention that research received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail (1 MB) Get e-AlertscloseSUBJECTS:Algorithms,Hydrogen,Infrared light,Molecules,Nuclear magnetic resonance spectroscopy e-Alerts

Language: Английский

Citations

7
Biological Polymers: Evolution, Function, and Significance DOI Creative Commons
Kavita Matange, Eric Marland, Moran Frenkel‐Pinter

et al.

Accounts of Chemical Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

ConspectusA holistic description of biopolymers and their evolutionary origins will contribute to our understanding biochemistry, biology, the life, signatures life outside planet. While biopolymer sequences evolve through known Darwinian processes, backbones polypeptides, polynucleotides, polyglycans are less certain. We frame this topic two questions: (i) Do characteristics indicate origins? (ii) Are there reasonable mechanistic models such pre-Darwinian processes? To address these questions, we have established criteria distinguish chemical species produced by mechanisms from those formed nonevolutionary physical, chemical, or geological processes. compile evaluate properties shared all rather than isolating a single type. Polypeptide, polynucleotide, polyglycan kinetically trapped thermodynamically unstable in aqueous media. Each forms variety elaborate assemblies with diverse functions, phenomenon call polyfunction. backbone changes structure function upon subtle as reduction ribose change linkage site stereochemistry polymerized glucose, function-switching. Biopolymers display homo- heterocomplementarity, enabling atomic-level control function. Biopolymer access recalcitrant states, where assembly modulates kinetics thermodynamics hydrolysis. emergent; biological building blocks significantly polymerization. In cells, compose mutualistic networks; cell is an Amazon Jungle molecules. conclude that exhibit hallmarks evolution. Neither nor processes can produce molecules consistent observations. faced paradox evolution relies on evolved but cannot alter backbones. This constraint underlined observation across tree ribosomes everywhere always been composed RNA protein. Our data suggest Hadean Earth underwent non-Darwinian coevolution driven part hydrolytic stress, ultimately leading argue highly facilitated seamless transition model challenges convention, products direct prebiotic synthesis. conventional models, retain vestiges chemistry. findings, however, align iterative recursive sculpting, selection, exaptation. supports Orgel's "gloomy" prediction modern biochemistry has discarded But hope. believe progress during challenging exciting integration sciences theory. These efforts provide new perspectives deepen sciences. working definition continuous exploration spaces avoidance equilibrium. alignment model, observe complex mixtures undergoing wet-dry cycling, which does appear undergo while avoiding

Language: Английский

Citations

1
Is the Emergence of Life an Expected Phase Transition in the Evolving Universe? DOI Open Access
Stuart Kauffman, Andrea Roli

Published: Jan. 17, 2024

We propose a novel definition of life in terms which its emergence the universe is expected, and ever-creative open-ended evolution entailed by no law. Living organisms are Kantian Wholes that achieve Catalytic Closure, Constraint Spatial Closure. here unite for first time two established mathematical theories, namely Collectively Autocatalytic Sets Theory Adjacent Possible. The former establishes first-order phase transition to molecular reproduction expected chemical where diversity complexity molecules increases; latter posits that, under loose hypotheses, if system starts with small number beginning molecules, each can combine copies itself or other make new over kinds increases slowly but then explodes upward hyperbolically. Together these theories imply as evolving universe. familiar distinction between software hardware loses meaning living cells. ways study phylogeny metabolisms, astronomical search on exoplanets, experiments seek most rudimentary life, hint coherent testable pathway prokaryotes template replication coding.

Language: Английский

Citations

6
Network motifs in cellular neurophysiology DOI
Divyansh Mittal, Rishikesh Narayanan

Trends in Neurosciences, Journal Year: 2024, Volume and Issue: 47(7), P. 506 - 521

Published: May 28, 2024

Language: Английский

Citations

5
A New Perspective on Tumor Progression: Evolution via Selection for Function DOI Creative Commons
Frédéric Thomas, James DeGregori, Andriy Marusyk

et al.

Evolution Medicine and Public Health, Journal Year: 2024, Volume and Issue: 12(1), P. 172 - 177

Published: Jan. 1, 2024

ABSTRACT Tumorigenesis is commonly attributed to Darwinian processes involving natural selection among cells and groups of cells. However, progressing tumors are those that also achieve an appropriate group phenotypic composition (GPC). Yet, the selective acting on tumor GPCs distinct from associated with classical evolution (i.e. based differential reproductive success) as not genuine evolutionary individuals do exhibit heritable variation in fitness. This complex scenario analogous recently proposed concept ‘selection for function’ invoked both living non-living systems. Therefore, we argue it inaccurate assert alone account all aspects characterizing tumorigenesis cancer progression; rather, by producing genetic diversity required creating novel GPCs, these fuel success dependent function at level.

Language: Английский

Citations

5
Updating functional brain units: Insights far beyond Luria DOI
Jordi Peña‐Casanova, Gonzalo Sánchez‐Benavides, Jorge Sigg-Alonso

et al.

Cortex, Journal Year: 2024, Volume and Issue: 174, P. 19 - 69

Published: Feb. 29, 2024

Language: Английский

Citations

4