Neurobiological basis of stress resilience

Neuron, Journal Year: 2024, Volume and Issue: 112(12), P. 1911 - 1929

Published: May 24, 2024

Language: Английский

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Validity of mental and physical stress models

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 158, P. 105566 - 105566

Published: Feb. 2, 2024

Language: Английский

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Heart–Brain Axis: A Narrative Review of the Interaction between Depression and Arrhythmia

Biomedicines, Journal Year: 2024, Volume and Issue: 12(8), P. 1719 - 1719

Published: Aug. 1, 2024

Arrhythmias and depression are recognized as diseases of the heart brain, respectively, both major health threats that often co-occur with a bidirectional causal relationship. The autonomic nervous system (ANS) serves crucial component heart–brain axis (HBA) pathway interoception. Cardiac activity can influence emotional states through ascending interoceptive pathways, while psychological stress precipitate arrhythmias via ANS. However, HBA interoception frameworks considered overly broad, precise mechanisms underlying relationship between remain unclear. This narrative review aims to synthesize existing literature, focusing on pathological ANS in arrhythmia integrating other potential detail interactions. In communication we emphasize considering various internal factors such genes, personality traits, stress, endocrine system, inflammation, 5-hydroxytryptamine, behavioral factors. Current research employs multidisciplinary knowledge elucidate relationships, deeper understanding these interactions help optimize clinical treatment strategies. From broader perspective, this study emphasizes importance body complex, interconnected rather than treating organs isolation. Investigating enhance our disease pathogenesis advances medical science, ultimately improving human quality life.

Language: Английский

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Risk and Protective Factors for the Evolution of Subthreshold Depression During Early Adolescence

Journal of Adolescent Health, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Molecular mechanism underlying stress response and adaptation

Progress in brain research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Resting-state fMRI reveals altered functional connectivity associated with resilience and susceptibility to chronic social defeat stress in mouse brain

Molecular Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Language: Английский

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Genetic, Epigenetic, and Hormonal Regulation of Stress Phenotypes in Major Depressive Disorder: From Maladaptation to Resilience

Cellular and Molecular Neurobiology, Journal Year: 2025, Volume and Issue: 45(1)

Published: March 26, 2025

Language: Английский

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Quality of Life and Well-Being in Women with Tetany Syndrome in the Context of Anxiousness and Stress Vulnerability

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(4), P. 358 - 358

Published: March 30, 2025

Background/Objectives: This paper deals with quality of life (QoL), mental well-being (WB), anxiousness, and stress vulnerability in women tetany syndrome (TS) comparison the population without syndrome. The aim is to investigate individual or combined effects vulnerability, diagnosis on women. Methods: research sample was composed 144 female (in terms sex) respondents a 123 females (comparative group). questionnaire battery used for data collection (WHOQoL-BREF, Warwick–Edinburgh scale, STAI (X-2), Stress Vulnerability Scale). In processing, comparisons, correlations, MANCOVA analyses were used. Results: group showed significantly lower levels (all domains) higher anxiousness compared stress, significant difference between groups not shown. Multivariate testing small interaction effect syndrome, life, while still had largest independent effect. Conclusions: Lifestyle aspects seem be possible intervening factor that, anxiety, contributes worse individuals results contribute perception psychological intervention, management support healthy lifestyle, as important addition mineral supplementation medication treatment.

Language: Английский

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The Locus Coeruleus: Anatomy, Physiology, and Stress‐Related Neuropsychiatric Disorders

European Journal of Neuroscience, Journal Year: 2025, Volume and Issue: 61(7)

Published: April 1, 2025

The locus coeruleus-norepinephrine (LC-NE) system is involved in mediating a wide array of functions, including attention, arousal, cognition, and stress response. Dysregulation the LC-NE strongly linked with several stress-induced neuropsychiatric disorders, highlighting LC's pivotal role development these disorders. Located dorsal pontine tegmental area, LC contains noradrenergic neurons that serve as main source NE central nervous system. Activation subsequent release at different levels neuroaxis adaptive, allowing body to adjust appropriately amid challenging stimulus. However, prolonged repeated activation leads maladaptive responses implicate dysfunction As primary initiator response, corticotropin-releasing factor (CRF) activates hypothalamic-pituitary-adrenal axis. Following discovery CRF more than four decades ago, numerous studies established also acts neurotransmitter governs activity other neurotransmitters brain receives abundant afferents arising from nuclei. are activated recruited pathogenesis Presented this review neuroanatomical connectivity physiological characteristics modulate function, which may contribute Additionally, illustrates contribution apparent sex-dependent differences Hence, promising target for therapeutic strategies

Language: Английский

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The relationship between psychological resilience and hair cortisol in adolescents: The influence of family and school environments

Psychoneuroendocrinology, Journal Year: 2025, Volume and Issue: unknown, P. 107471 - 107471

Published: April 1, 2025

Language: Английский

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