Biofabrication,
Journal Year:
2024,
Volume and Issue:
17(1), P. 015042 - 015042
Published: Dec. 16, 2024
Abstract
Lung
cancer
is
a
serious
global
health
issue
that
requires
the
development
of
patient-specific,
lung
model
for
surgical
planning
to
train
interventionalists
and
improve
accuracy
biopsies.
Although
emergence
three-dimensional
(3D)
printing
provides
promising
solution
create
customized
models
with
complicated
architectures,
current
3D
methods
cannot
accurately
duplicate
anatomical-level
constructs
tumor(s)
which
are
applicable
hands-on
training
procedure
planning.
To
address
this
issue,
an
embedded
strategy
proposed
respiratory
bronchioles,
blood
vessels,
tumors
in
photocurable
yield-stress
matrix
bath.
After
crosslinking,
patient-specific
analogous
produced,
has
tunable
transparency
mechanical
properties
mimic
parenchyma.
This
engineered
not
only
enables
practical
fine-needle
aspiration
biopsy
but
also
necessary
information,
such
as
coordinates
aspiration,
wound
depth,
interference
surrounding
tissues,
optimization.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 21, 2025
Abstract
Mechanical
information
is
a
medium
for
perceptual
interaction
and
health
monitoring
of
organisms
or
intelligent
mechanical
equipment,
including
force,
vibration,
sound,
flow.
Researchers
are
increasingly
deploying
recognition
technologies
(MIRT)
that
integrate
acquisition,
pre‐processing,
processing
functions
expected
to
enable
advanced
applications.
However,
this
also
poses
significant
challenges
acquisition
performance
efficiency.
The
novel
exciting
mechanosensory
systems
in
nature
have
inspired
us
develop
superior
bionic
(MIBRT)
based
on
materials,
structures,
devices
address
these
challenges.
Herein,
first
strategies
pre‐processing
presented
their
importance
high‐performance
highlighted.
Subsequently,
design
considerations
sensors
by
mechanoreceptors
described.
Then,
the
concepts
neuromorphic
summarized
order
replicate
biological
nervous
system.
Additionally,
ability
MIBRT
investigated
recognize
basic
information.
Furthermore,
further
potential
applications
robots,
healthcare,
virtual
reality
explored
with
view
solve
range
complex
tasks.
Finally,
future
opportunities
identified
from
multiple
perspectives.
Virtual and Physical Prototyping,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: Aug. 5, 2024
Organ
transplantation
is
the
optimal
treatment
for
patients
with
end-stage
organ
failure,
but
which
faces
challenge
of
donor
shortage.
Two-dimensional
cell
culture
and
animal
experiments
are
difficult
to
completely
simulate
complex
cellular
microenvironment
drug
testing.
Three-dimensional
(3D)
bioprinting
an
emerging
manufacturing
technology
fabricate
artificial
tissues
organs
screening.
This
review
first
describes
technologies
used
constructs,
including
jetting-based,
extrusion-based,
vat
photopolymerization-based
methods
other
3D
approaches.
The
various
kinds
bioinks,
sources,
most
recent
applications
in
testing
subsequently
summarized.
Finally,
we
discuss
challenges
prospects
organs.
aims
facilitate
overcoming
obstacles
identified
on
challenging
journey
towards
adoption
tissue
Advanced Materials Technologies,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 7, 2025
Abstract
Embedded
ink
writing
(EIW)
is
an
emerging
3D
printing
technique
that
extensively
applied
for
a
variety
of
engineering
applications.
This
featured
by
liquid
functional
within
yield‐stress
fluid
bath.
Due
to
the
selection
and
bath
materials
with
different
hydrophilicity
hydrophobicity,
diverse
ink‐bath
interactions
occur
affect
filament
formation
in
EIW.
In
this
work,
interrelationships
between
three
major
physical
phenomena
(including
diffusion,
shrinkage,
breakage)
are
experimentally
systematically
investigated.
Several
key
parameters,
such
as
interfacial
tension
materials,
ink's
elasticity,
bath's
yield
stress,
significantly
morphology
and/or
geometry
as‐printed
filaments.
Based
on
obtained
knowledge,
index
finger
printed,
which
demonstrates
good
grasping
capability
robotic
hand
system.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101505 - 101505
Published: Jan. 22, 2025
Cardiac
organoids
offer
sophisticated
3D
structures
that
emulate
key
aspects
of
human
heart
development
and
function.
This
review
traces
the
evolution
cardiac
organoid
technology,
from
early
stem
cell
differentiation
protocols
to
advanced
bioengineering
approaches.
We
discuss
methodologies
for
creating
organoids,
including
self-organization
techniques,
biomaterial-based
scaffolds,
bioprinting,
organ-on-chip
platforms,
which
have
significantly
enhanced
structural
complexity
physiological
relevance
in
vitro
models.
examine
their
applications
fundamental
research
medical
innovations,
highlighting
potential
transform
our
understanding
biology
pathology.
The
integration
multiple
types,
vascularization
strategies,
maturation
has
led
more
faithful
representations
adult
heart.
However,
challenges
remain
achieving
full
functional
maturity
scalability.
critically
assess
current
limitations
outline
future
directions
advancing
technology.
By
providing
a
comprehensive
analysis
field,
this
aims
catalyze
further
innovation
tissue
engineering
facilitate
its
translation
clinical
applications.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 11, 2025
Abstract
Embedded
ink
writing
(EIW)
is
an
emerging
3D
printing
technique
that
fabricates
complex
structures
from
various
biomaterial
inks
but
limited
to
a
speed
of
∼10
mm
s
−1
due
suboptimal
rheological
properties
particulate‐dominated
yield‐stress
fluids
when
used
as
liquid
baths.
In
this
work,
particle‐hydrogel
interactive
system
design
advanced
baths
with
enhanced
yield
stress
and
extended
thixotropic
response
time
for
realizing
high‐speed
EIW
developed.
system,
the
interactions
between
particle
additive
three
representative
polymeric
hydrogels
enable
resulting
nanocomposites
demonstrate
different
behaviors.
Accordingly,
interaction
models
are
established,
which
subsequently
validated
by
macroscale
measurements
microstructure
characterization
techniques.
Filament
formation
mechanisms
in
comprehensively
investigated
at
high
speeds.
To
effectiveness
proposed
method,
anatomic‐size
human
kidney
construct
successfully
printed
110
,
only
takes
∼4
h.
This
work
breaks
barrier
current
propels
maximum
least
10
times,
providing
efficient
promising
solution
organ
reconstruction
future.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: July 10, 2024
Corneal
opacity
is
one
of
the
leading
causes
severe
vision
impairment.
transplantation
dominant
therapy
for
irreversible
corneal
blindness.
However,
there
a
worldwide
shortage
donor
grafts
and
consequently
an
urgent
demand
alternatives.
Three-dimensional
(3D)
bioprinting
innovative
additive
manufacturing
technology
high-resolution
distribution
bioink
to
construct
human
tissues.
The
has
shown
great
promise
in
field
bone,
cartilage
skin
tissue
construction.
3D
allows
precise
structural
construction
functional
cell
printing,
which
makes
it
possible
print
personalized
full-thickness
or
lamellar
layers.
Seed
cells
play
important
role
producing
biological
functions.
And
stem
are
potential
seed
In
this
review,
basic
anatomy
physiology
natural
cornea
keratoplasties
introduced.
Then,
applications
techniques
bioinks
their
interaction
with
reviewed,
both
application
promising
future
engineering
discussed.
Finally,
development
trends
requirements
challenges
using
as
graft
summarized,
directions
suggested.
Gels,
Journal Year:
2024,
Volume and Issue:
10(10), P. 644 - 644
Published: Oct. 10, 2024
Constructing
tissue/organ
analogs
with
natural
structures
and
cell
types
in
vitro
offers
a
valuable
strategy
for
the
situ
repair
of
damaged
tissues/organs.
Three-dimensional
(3D)
bioprinting
is
flexible
method
fabricating
these
analogs.
However,
extrusion-based
3D
faces
challenge
balancing
use
soft
bioinks
need
high-fidelity
geometric
shapes.
To
address
challenges,
recent
advancements
have
introduced
various
suspension
mediums
based
on
gelatin,
agarose,
gellan
gum
microgels.
The
emergence
gel-based
has
significantly
advanced
fabrication
constructs
using
bioprinting.
They
effectively
stabilize
support
bioinks,
enabling
formation
complex
spatial
geometries.
Moreover,
they
provide
stable,
cell-friendly
environment
that
maximizes
viability
during
printing
process.
This
minireview
will
summarize
properties,
preparation
methods,
potential
applications
constructing
analogs,
while
also
addressing
current
challenges
providing
an
outlook
future
