Architectural dissection of adhesive bacterial cell surface appendages from a “molecular machines” viewpoint DOI Creative Commons
Olivia E. R. Smith, Tanmay A. M. Bharat

Journal of Bacteriology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

ABSTRACT The ability of bacteria to interact with and respond their environment is crucial lifestyle survival. Bacterial cells routinely need engage extracellular target molecules, in locations spatially separated from cell surface. Engagement distant targets allows adhere abiotic surfaces host cells, sense harmful or friendly molecules vicinity, as well establish symbiotic interactions neighboring multicellular communities such biofilms. Binding also facilitates transmission information back the originating cell, allowing appropriately external stimuli, which critical throughout bacterial life cycle. This requirement bind fulfilled by a myriad specialized surface often have an extended, filamentous arrangement. In this review, we compare contrast diverse bacteria, fulfil range binding functions for cell. Our comparison shows that even though these extended vastly different sequence, biochemical functional characteristics, they share common architectural principles underpin adhesion variety contexts. light, can consider adhesins under one umbrella, specifically point view modular molecular machine, each part fulfilling distinct role. Such treatise provides opportunity discover fundamental governing sensing, adhesion, biofilm formation.

Language: Английский

Architectural dissection of adhesive bacterial cell surface appendages from a “molecular machines” viewpoint DOI Creative Commons
Olivia E. R. Smith, Tanmay A. M. Bharat

Journal of Bacteriology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

ABSTRACT The ability of bacteria to interact with and respond their environment is crucial lifestyle survival. Bacterial cells routinely need engage extracellular target molecules, in locations spatially separated from cell surface. Engagement distant targets allows adhere abiotic surfaces host cells, sense harmful or friendly molecules vicinity, as well establish symbiotic interactions neighboring multicellular communities such biofilms. Binding also facilitates transmission information back the originating cell, allowing appropriately external stimuli, which critical throughout bacterial life cycle. This requirement bind fulfilled by a myriad specialized surface often have an extended, filamentous arrangement. In this review, we compare contrast diverse bacteria, fulfil range binding functions for cell. Our comparison shows that even though these extended vastly different sequence, biochemical functional characteristics, they share common architectural principles underpin adhesion variety contexts. light, can consider adhesins under one umbrella, specifically point view modular molecular machine, each part fulfilling distinct role. Such treatise provides opportunity discover fundamental governing sensing, adhesion, biofilm formation.

Language: Английский

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