Published: July 29, 2024
As a key member of the neurotrophin family in central nervous system, brain-derived neurotrophic factor (BDNF) plays critical role maintenance and plasticity system. Its innate neuroprotective advantage can also be shared with brain when normal aging-dependent processes challenge neural circuits. The intricate relationship between BDNF resilience during aging process signifies molecular mechanisms that underlie protection function, such as cognition, movement psychological well-being. is crucial for neuronal growth survival, it promote against age-related functional decline frailty, even if fails to entirely prevent ageing-related decline. In present review, we discuss function from perspective how may aging. We emphasize briefly principal, well-known cellular hallmarks restrict disabling dynamics enhance overall Insight into pathways through which reduces dysfunctions and/or improves resilience, provide foundation developing targeted interventions mental well-being an population.
Language: Английский