BIFROST: A method for registering diverse imaging datasets of the Drosophila brain DOI Creative Commons

Bella E. Brezovec,

Andrew B. Berger,

Yukun A. Hao

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(47)

Published: Nov. 14, 2024

Imaging methods that span both functional measures in living tissue and anatomical fixed have played critical roles advancing our understanding of the brain. However, making direct comparisons between different imaging modalities, particularly spanning tissue, has remained challenging. For example, comparing brain-wide neural dynamics across experiments aligning such data to resources, as gene expression patterns or connectomes, requires precise alignment a common set coordinates. reaching this goal is difficult because registering vivo ex reference atlases accommodating differences modality, microscope specification, sample preparation. We overcome these challenges

Language: Английский

BIFROST: A method for registering diverse imaging datasets of the Drosophila brain DOI Creative Commons

Bella E. Brezovec,

Andrew B. Berger,

Yukun A. Hao

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(47)

Published: Nov. 14, 2024

Imaging methods that span both functional measures in living tissue and anatomical fixed have played critical roles advancing our understanding of the brain. However, making direct comparisons between different imaging modalities, particularly spanning tissue, has remained challenging. For example, comparing brain-wide neural dynamics across experiments aligning such data to resources, as gene expression patterns or connectomes, requires precise alignment a common set coordinates. reaching this goal is difficult because registering vivo ex reference atlases accommodating differences modality, microscope specification, sample preparation. We overcome these challenges

Language: Английский

Citations

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