Active fluctuations of axoneme oscillations scale with number of dynein motors DOI Creative Commons
Abhimanyu Sharma, Benjamin M. Friedrich, Veikko F. Geyer

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(46)

Published: Nov. 5, 2024

Fluxes of energy generate active forces in living matter, yet also fluctuations. As a canonical example, collections molecular motors exhibit spontaneous oscillations with frequency jitter caused by nonequilibrium phase We investigate fluctuations reactivated Chlamydomonas reinhardtii axonemes, which are accessible to direct manipulation. quantify the precision axonemal after controlled chemical removal dynein motors, providing an experimental test for theory prediction that quality factor motor should increase number. Our quantification reveals specialized roles inner and outer arm motors. This supports model dyneins serve as master pace-makers, become entrained, consistent recent insight provided structural biology.

Language: Английский

Active fluctuations of axoneme oscillations scale with number of dynein motors DOI Creative Commons
Abhimanyu Sharma, Benjamin M. Friedrich, Veikko F. Geyer

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(46)

Published: Nov. 5, 2024

Fluxes of energy generate active forces in living matter, yet also fluctuations. As a canonical example, collections molecular motors exhibit spontaneous oscillations with frequency jitter caused by nonequilibrium phase We investigate fluctuations reactivated Chlamydomonas reinhardtii axonemes, which are accessible to direct manipulation. quantify the precision axonemal after controlled chemical removal dynein motors, providing an experimental test for theory prediction that quality factor motor should increase number. Our quantification reveals specialized roles inner and outer arm motors. This supports model dyneins serve as master pace-makers, become entrained, consistent recent insight provided structural biology.

Language: Английский

Citations

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