Comprehensive Evaluation of the Analytical Efficiency of Combustion Ion Chromatography for Per- and Polyfluoroalkyl Substances in Biological and Environmental Matrices

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Combustion ion chromatography (CIC) has emerged as a valuable tool for determining fluorine content attributable to per- and polyfluoroalkyl substances (PFAS) in biological environmental samples. The total organofluorine (TOF) data from CIC complement information obtained by targeted analyses using liquid chromatography-tandem mass spectrometry (LC–MS/MS) because TOF includes PFAS that may not be captured techniques. However, the effect of different types (chain lengths, head groups, etc.) matrices on combustion efficiency been systematically evaluated. Comparison C4–C12 equimolar quantities (5.27 nmol F) demonstrated statistically equivalent responses, indicating uniform across chain lengths. Further, signals resulting times ranging 7.5 15 min were equivalent. fluorotelomer alcohols (FTOHs) exhibited losses due volatility, requiring use an activated carbon sorbent improve analytical signals. Matrix variations no change lengths water, blood, biosolids. Total results analysis real blood biosolid samples compared LC–MS/MS results. This study highlights strengths limitations important provide guidance optimizing application-specific conditions interpreting

Language: Английский

Key developments in fluorinated heterocycles

Future Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 2

Published: March 6, 2025

Language: Английский

Interactions between Perfluorinated Alkyl Substances (PFAS) and Microplastics (MPs): Findings from an Extensive Investigation

Journal of Hazardous Materials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100740 - 100740

Published: May 1, 2025

Language: Английский