Chitosan Rheological Behavior in an Acidic Water Mixture for Pharmaceutical and Biomedical Applications DOI

Afef Ben Yahya,

Emna Cherif

Journal of Macromolecular Science Part B, Journal Year: 2023, Volume and Issue: 63(10), P. 972 - 984

Published: Dec. 25, 2023

The importance of chitosan (CH) has grown significantly over the last two decades due to its renewable and biodegradable source, also because recent increase in our knowledge functionality technological biomedical applications. present article reviews biopolymer CH derivatives, as versatile biomaterials for potential drug delivery systems, well tissue engineering applications, analgesia treatment arthritis. natural antimicrobial agents, can be applied biomedical, biotechnological, pharmaceutical Its activity depends on many factors such molecular size, associated components, concentration, type microorganism. In research described here we prepared characterized dynamic viscosity rheological properties a material based solution acidic water. shear stress were measured under influence an increasing concentration 1–10 g/l temperature 288.15–318.15 K.

Language: Английский

Chitosan and sodium carboxymethylcellulose biocomplex interaction properties for biomedical and pharmaceutical applications DOI

Eya Chikhaoui,

Emna Cherif,

Étienne Herth

et al.

Phase Transitions, Journal Year: 2024, Volume and Issue: 97(3), P. 212 - 227

Published: Jan. 4, 2024

The naturally occurring polymers chitosan (CH) and sodium carboxymethylcellulose (CMC) have attracted the interest of researchers in a variety biomedical pharmaceutical applications such as drug delivery, cosmetics, tissue engineering. However, CMC CH certain limitations for use controlled aqueous CMC/CH mixed solutions. In this study, solutions with same concentration 0.5 g/l pH 6 are under atmospheric conditions. effects temperature molar volume fraction X1 on decreased electrical conductivity were studied at different temperatures ranging from 15°C to 80°C. We highlighted that regions can be distinguished complexes, depending composition electrostatic interactions solutions, which associated significantly phase behaviors.

Language: Английский

Citations

5

Exploring Interactions and Properties of the Sodium Carboxymethyl Cellulose–Chitosan Biopolymer Complex DOI

Wiem Ardhaoui,

Emna Cherif,

Étienne Herth

et al.

physica status solidi (a), Journal Year: 2024, Volume and Issue: 221(5)

Published: Jan. 26, 2024

The complex of sodium carboxymethyl cellulose (CMC) and chitosan (CH) in aqueous solution can be used for biomedical applications is very beneficial tissue engineering, drug delivery, disease treatment. This article presents elaboration properties the two polysaccharides with opposite charges CMC/CH solutions. electrical conductivity under influence increasing concentrations mixtures from (0.5 to 10) g l −1 temperatures 288.15 318.15 K investigated. reduced conductivities, , energy activation Gibbs free activations parameters enthalpy () entropy are estimated.

Language: Английский

Citations

5

The drug paracetamol and sodium carboxymethyl cellulose/polyvinyl alcohol composites, interactions for pharmaceutical and biomedical applications DOI

Emna Cherif,

Eya Chikhaoui

Physics and Chemistry of Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: April 4, 2025

Language: Английский

Citations

0

Calcium Chloride’s Impact on the Behavior of Sodium Carboxymethylcellulose in Water Mixtures for Pharmaceutical and Biomedical Uses DOI

Emna Cherif,

Eya Chikhaoui

Journal of Macromolecular Science Part B, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: April 5, 2025

Language: Английский

Citations

0

The Drug Paracetamol and Sodium Carboxymethyl Cellulose Interactions and Their Importances for Pharmaceutical and Biomedical Applications DOI

Hamida Moumni,

Emna Cherif

Journal of Macromolecular Science Part B, Journal Year: 2024, Volume and Issue: 63(11), P. 1189 - 1202

Published: Feb. 14, 2024

The interactions of naturally occurring polymers and medicaments, sodium carboxymethyl cellulose (Na-CMC) Paracetamol (PCM), have attracted the interest researchers in a variety biomedical pharmaceutical applications areas, such as drug delivery, cosmetics tissue engineering. In our research described here, effects temperature concentration Na-CMC/PCM/water (W) mixed solutions were studied at various temperatures ranging from 20 °C to 45 °C. We highlighted that different regions can be distinguished aqueous Na-CMC/PCM/W complexes, depending on composition electrostatic solutions, which are associated with significantly phase behaviors.

Language: Английский

Citations

3

Rheological and film-forming properties of carboxymethylcellulose and polyvinyl alcohol (CMC/PVA) mixtures DOI

Eya Chikhaoui,

Emna Cherif,

Mehdi Ammar

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126819 - 126819

Published: Dec. 1, 2024

Language: Английский

Citations

2

Sodium Carboxymethylcellulose Rheological Behavior in a Water Mixture for Pharmaceutical and Biomedical Applications DOI

Hamida Moumni,

Emna Cherif

Journal of Macromolecular Science Part B, Journal Year: 2024, Volume and Issue: 63(10), P. 941 - 956

Published: Jan. 2, 2024

Sodium carboxymethylcellulose Na-CMC is derived from cellulose fibers. Knowledge of the behavior as a charged polysaccharide in solution important, because most its biomedical industrial applications utilize solutions. The main objective our research described here was to determine rheological and viscometric properties solutions water (W), function cutting speed polymer concentration. evolution reduced dynamic viscosities effect Gibbs energy W were characterized temperature (15 °C 45 °C), concentration (1 10) g/l. We identified three regimes, corresponding dilute regime, critical semi-dilute regime. thermodynamic parameters viscosity also supported obtained results. Our results show that Na-CMC/W promising solvent mixture for use pharmaceutical antibacterial applications.

Language: Английский

Citations

1

The correlation properties of polyethylene glycol in dimethyl sulphoxide by viscosimetric study DOI

Eya Chikhaoui,

Emna Cherif

Physics and Chemistry of Liquids, Journal Year: 2023, Volume and Issue: 62(4), P. 248 - 257

Published: Dec. 22, 2023

This paper presents the experimental analysis of viscosimetric properties poly(ethylene glycol) (PEG) in dimethyl sulphoxide DMSO. By study solutions PEG/DMSO, dynamic viscosity was measured under influence increasing PEG concentration (1 g/l to 10 g/l) and temperature (15°C 45°C). The reduced activation energy Eη are calculated. polymer exhibited a critical c**, separating dilute into extremely solutions. most important results refer found from Arrhenius plots. dependence on solution is discussed. behaviour can be extrapolated Flory-Huggins theory by decomposing such as = (Eη)ex di + (Eη)di (Eη)cri. described PEG-DMSO interaction represented function di. For non-Arrhenius which between PEG-PEG (Eη)di. interactions Principles that aid one understand interpret

Language: Английский

Citations

2

Chitosan and Poly(N-vinyl-pyrrolidone) Interaction Properties. Pharmaceutical and Biomedical Applications DOI

Afef Ben Yahya,

Zina Ameddeb,

Emna Cherif

et al.

Journal of Macromolecular Science Part B, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: May 3, 2024

The naturally occurring polymers, chitosan (CH) and poly(N-vinyl-pyrrolidone (PVP), have attracted the interest of researchers in a variety biomedical pharmaceutical applications areas, such as drug delivery, cosmetics, tissue engineering. However, PVP CH certain limitations for use controlled aqueous CH/PVP mixed solutions. In this study solutions with same concentration 10 g/l pH 6 were under atmospheric conditions. effects temperature molar volume fraction, X1, on decreased dynamic viscosity studied at various temperatures ranging from 15 °C to 80 °C. We highlighted that different regions can be distinguished complexes, depending composition electrostatic interactions solutions, which are associated significantly phase behaviors.

Language: Английский

Citations

0

The properties of chitosan and paracetamol in acidic water mixture by viscosity study for pharmaceutical and biomedical applications DOI

Afef Ben Yahya,

Emna Cherif

Physics and Chemistry of Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 10

Published: May 23, 2024

Paracetamol (PC), the active ingredient in Efferalgan, is an effervescent tablet medicine used treatment of mild-to-moderate pain. Chitosan (CH) a biopolymer having immense structural possibilities for chemical and mechanical modifications to generate novel properties, functions applications, especially pharmaceutical area. The dynamic viscosities, η, have been measured, investigated mixture CH acidic water paracetamol aqueous solutions over entire range temperature 20–65°C, concentrations 1–10 g/l. main objective our research described here was determine viscometric properties PC, as function volume fraction fCH PC temperatures. We identified three concentration regimes, corresponding dilute regime, critical regime semi-dilute regime. Our results showed that CH/PC promising use antibacterial applications. chitosan shows antimicrobial activity against various microorganisms, including bacteria.

Language: Английский

Citations

0