Membrane Permeability and Drug Targeting Potential of Phospholipid‐Based Nanocarriers in Lung Cancer Therapy DOI
Olivia Sen, Poulami Sarkar, Stabak Das

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(40)

Published: Oct. 1, 2024

Abstract Lung cancer has become the leading cause of cancer‐related deaths, surpassing all other forms cancer. Among lung cancers, non‐small cell (NSCLC) accounts for approximately 85% cases. The use tobacco, genetic traits, and radiation exposure are amongst major reasons ongoing research in medical field considered efficacy nanocarriers targeting various cells. several biomaterials, lipid‐based have gained special attention due to their excellent compatibility, improved efficacy, encapsulation ability diverse therapeutic agents. Phospholipids naturally occurring amphiphilic moieties found living creatures. presence phospholipids biomembrane aids permeability phospholipid‐based drug carrier. It can also facilitate agents microenvironment without degrading encapsulated drug. be employed develop conjugated vesicular nanoformulation that result prolonged circulatory half‐life controlled release drugs. suitable biomaterials attach a ligand tissue‐specific targeting. Recent researches reported effective chemotherapeutic agents, genes, vaccines through This review focuses on rationality applications therapy.

Language: Английский

Hierarchical chitin and chitosan-derived heterostructural nanocomposites: From interdisciplinary applications to a sustainable vision DOI
Le Gia Trung,

Jin Seog Gwag,

Ha Huu

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 362, P. 123702 - 123702

Published: May 5, 2025

Language: Английский

Citations

0
Pet-coke derived GO/Chitosan Polymer Composite: Preparation, Characterization, and Biomedical Evaluation. DOI

S. Renukadevi,

V Manimozhi,

Sivakumar E. K .T Sivakumar E. K .T

et al.

Journal of the Indian Chemical Society, Journal Year: 2025, Volume and Issue: unknown, P. 101760 - 101760

Published: May 1, 2025

Language: Английский

Citations

0
Therapeutic Efficacy of Nanocarrier‐Mediated Inhalable Gene Transfection for Lung Cancer DOI
Poulami Sarkar,

M. Rizwan Sardar,

Olivia Sen

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(37)

Published: Oct. 1, 2024

Abstract Lung cancer is now the leading cause of cancer‐related mortality, eclipsing all other forms, and lung malignancies, non‐small cell (NSCLC) makes up around 85%. Recently, use vectors in gene therapy besides chemotherapy to treat malignancies brought on by mutations has gained prominence. Therapeutic molecule inhalation a direct approach lung‐targeted medication delivery with low nonspecific toxicity limited drug exposure. Treatment for immunotherapy can be aided inhalable nanomedicine through advanced mechanisms. Viral nonviral vectors, such as lipid‐based nanoparticles, polymeric inorganic have drawn lot interest their ability increase effects decrease side effects. Nanocarriers significant impact targeted delivery, bioavailability, stability, residence target areas. The inhaled pulmonary approach, when combined nanomedicine, will offer noninvasive successful way taking physiological properties lung. authors majorly used data from PubMed Google Scholar obtain relevant information required article. In general, this review concentrates usage various nanocarriers, which might serve an inspiration creation deployment more potent genetic treatment cancer.

Language: Английский

Citations

2
Membrane Permeability and Drug Targeting Potential of Phospholipid‐Based Nanocarriers in Lung Cancer Therapy DOI
Olivia Sen, Poulami Sarkar, Stabak Das

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(40)

Published: Oct. 1, 2024

Abstract Lung cancer has become the leading cause of cancer‐related deaths, surpassing all other forms cancer. Among lung cancers, non‐small cell (NSCLC) accounts for approximately 85% cases. The use tobacco, genetic traits, and radiation exposure are amongst major reasons ongoing research in medical field considered efficacy nanocarriers targeting various cells. several biomaterials, lipid‐based have gained special attention due to their excellent compatibility, improved efficacy, encapsulation ability diverse therapeutic agents. Phospholipids naturally occurring amphiphilic moieties found living creatures. presence phospholipids biomembrane aids permeability phospholipid‐based drug carrier. It can also facilitate agents microenvironment without degrading encapsulated drug. be employed develop conjugated vesicular nanoformulation that result prolonged circulatory half‐life controlled release drugs. suitable biomaterials attach a ligand tissue‐specific targeting. Recent researches reported effective chemotherapeutic agents, genes, vaccines through This review focuses on rationality applications therapy.

Language: Английский

Citations

0