Nephroprotective effects of substances of medicine food homology and traditional Chinese medicine phytochemicals against acute kidney injury

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 19, 2025

Acute kidney injury (AKI) represents significant medical challenges due to its elevated rates of morbidity and mortality, with limited therapeutic options currently available. Hence, the exploration novel medicinal treatments for AKI management remains vital. Substances medicine food homology (SMFH), referring substances having characteristics both medicine, have been applied in China thousands years.They could be used daily diets body conditioning. Traditional Chinese (TCM), naturally derived components demonstrated effectiveness, presents distinctive benefits treatment. Numerous studies shown that SMFH TCM phytochemicals function satisfactorily nephroprotective effects a effect on alleviating as well complications. In this review, pathogenesis was illustrated. We concentrated against tried summarize underlying mechanisms various kinds AKI, highlighting crucial phytochemical prevention therapy. Besides, strategies globalization are analysed. This review comprehensively reveals exhibit promising potential intervention by targeting signal pathways targets, which would contribute AKI's cognition, preventive treatments, global promotion.

Language: Английский

Transformative Potentials, Challenges and Innovative Solutions of Lipidomics in Multiple Clinical Applications

Talanta, Journal Year: 2025, Volume and Issue: 291, P. 127855 - 127855

Published: Feb. 27, 2025

Language: Английский