Advancements in Materials for 3D-Printed Microneedle Arrays: Enhancing Performance and Biocompatibility
Mahmood Razzaghi,
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Joel Alexander Ninan,
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Mohsen Akbari
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et al.
Micromachines,
Journal Year:
2024,
Volume and Issue:
15(12), P. 1433 - 1433
Published: Nov. 28, 2024
The
rapid
advancement
of
3D
printing
technology
has
revolutionized
the
fabrication
microneedle
arrays
(MNAs),
which
hold
great
promise
in
biomedical
applications
such
as
drug
delivery,
diagnostics,
and
therapeutic
interventions.
This
review
uniquely
explores
advanced
materials
used
production
3D-printed
MNAs,
including
photopolymer
resins,
biocompatible
materials,
composite
designed
to
improve
mechanical
properties,
biocompatibility,
functional
performance.
Additionally,
it
introduces
emerging
trends
4D
for
programmable
MNAs.
By
analyzing
recent
innovations,
this
identifies
critical
challenges
proposes
future
directions
advance
field
Unlike
previous
reviews,
paper
emphasizes
integration
innovative
with
techniques
enhance
both
performance
sustainability
Language: Английский
A Feasibility Study on the Use of UV‐Curable Resins for Long‐Acting Monitoring Microneedle Substrates
Baoling Jia,
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Tiandong Xia,
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Xiaohui Wang
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et al.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(12)
Published: Dec. 1, 2024
ABSTRACT
Microneedle
(MN)
has
significant
potential
for
transdermal
glucose
monitoring.
However,
challenges
remain
in
selecting
suitable
materials
long‐acting
monitoring
MN.
In
this
study,
precise
solid
UV‐curable
resin
MN
patches
were
fabricated
using
a
synergistic
combination
of
the
micromolding
method
and
UV‐curing
procedure,
as
an
alternative
to
previous
3D
printing.
The
properties
UV‐cured
prepared
evaluated
characterized,
focusing
on
their
results
demonstrated
that
exhibited
superior
shape
stability,
very
low
cytotoxicity,
minimal
skin
irritation,
fracture
force
approximately
2.289
N/needle.
Following
immersion
37°C
PBS
different
days,
mass
changed
negligibly,
still
reached
half
original
values
after
21
days.
is
highly
promising
substrate
MN,
study
provides
new
material
selection
strategy
development.
Language: Английский