A Feasibility Study on the Use of UV‐Curable Resins for Long‐Acting Monitoring Microneedle Substrates DOI
Baoling Jia,

Tiandong Xia,

Xiaohui Wang

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT Microneedle (MN) has significant potential for transdermal glucose monitoring. However, challenges remain in selecting suitable materials long‐acting monitoring MN. In this study, precise solid UV‐curable resin MN patches were fabricated using a synergistic combination of the micromolding method and UV‐curing procedure, as an alternative to previous 3D printing. The properties UV‐cured prepared evaluated characterized, focusing on their results demonstrated that exhibited superior shape stability, very low cytotoxicity, minimal skin irritation, fracture force approximately 2.289 N/needle. Following immersion 37°C PBS different days, mass changed negligibly, still reached half original values after 21 days. is highly promising substrate MN, study provides new material selection strategy development.

Language: Английский

Advancements in Materials for 3D-Printed Microneedle Arrays: Enhancing Performance and Biocompatibility DOI Creative Commons
Mahmood Razzaghi,

Joel Alexander Ninan,

Mohsen Akbari

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(12), P. 1433 - 1433

Published: Nov. 28, 2024

The rapid advancement of 3D printing technology has revolutionized the fabrication microneedle arrays (MNAs), which hold great promise in biomedical applications such as drug delivery, diagnostics, and therapeutic interventions. This review uniquely explores advanced materials used production 3D-printed MNAs, including photopolymer resins, biocompatible materials, composite designed to improve mechanical properties, biocompatibility, functional performance. Additionally, it introduces emerging trends 4D for programmable MNAs. By analyzing recent innovations, this identifies critical challenges proposes future directions advance field Unlike previous reviews, paper emphasizes integration innovative with techniques enhance both performance sustainability

Language: Английский

Citations

3
A Feasibility Study on the Use of UV‐Curable Resins for Long‐Acting Monitoring Microneedle Substrates DOI
Baoling Jia,

Tiandong Xia,

Xiaohui Wang

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT Microneedle (MN) has significant potential for transdermal glucose monitoring. However, challenges remain in selecting suitable materials long‐acting monitoring MN. In this study, precise solid UV‐curable resin MN patches were fabricated using a synergistic combination of the micromolding method and UV‐curing procedure, as an alternative to previous 3D printing. The properties UV‐cured prepared evaluated characterized, focusing on their results demonstrated that exhibited superior shape stability, very low cytotoxicity, minimal skin irritation, fracture force approximately 2.289 N/needle. Following immersion 37°C PBS different days, mass changed negligibly, still reached half original values after 21 days. is highly promising substrate MN, study provides new material selection strategy development.

Language: Английский

Citations

0