Feasibility of telephone and computerized cognitive testing as a secondary outcome in an acute stroke clinical trial: A mixed methods sub-study of the AcT Trial DOI Creative Commons
Sajeevan Sujanthan,

Pugaliya Puveendrakumaran,

Katie N. Dainty

et al.

European Stroke Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Introduction: Post-stroke cognitive impairment is associated with impaired quality of life. Remote testing provides a potential avenue to measure outcomes efficiently. Patients and Methods: Prospective were collected at 90–180 days using both telephone MoCA (T-MoCA; range 0–22; <17 impairment) Creyos, computerized battery. Key variables completion assessed logistic regressions. Mixed methods brief structured interviews exit survey performed explore barriers completing computer testing. Results: Of 791 potentially eligible patients (mean age 70 ± 14 years), there was low feasibility remote testing, only 401 (51%) the T-MoCA, 242 (31%) Creyos. Our regression models show that (OR T-MoCA : 0.95 (95% Confidence Interval (CI): 0.94–0.97); OR Creyos CI: 0.94–0.96)), functional (mRS 2–5; 0.55 0.37–0.81); 0.66 0.44–0.98)), life (EQ-VAS; 1.02 1.01–1.03); OR:1.02 1.01–1.03)) length hospital stay 0.98 0.96–0.99); 0.97 0.94–0.99)) predicted test completion; literacy 1.12 1.04–1.21)). In interviews, preference for accessibility reported. Discussion: has limited as secondary outcome in large acute stroke trials. who are older, worse life, or severe post-stroke less likely complete outcomes. Conclusion: Innovative approaches trials needed. Data Access available upon request.

Language: Английский

Feasibility of telephone and computerized cognitive testing as a secondary outcome in an acute stroke clinical trial: A mixed methods sub-study of the AcT Trial DOI Creative Commons
Sajeevan Sujanthan,

Pugaliya Puveendrakumaran,

Katie N. Dainty

et al.

European Stroke Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Introduction: Post-stroke cognitive impairment is associated with impaired quality of life. Remote testing provides a potential avenue to measure outcomes efficiently. Patients and Methods: Prospective were collected at 90–180 days using both telephone MoCA (T-MoCA; range 0–22; <17 impairment) Creyos, computerized battery. Key variables completion assessed logistic regressions. Mixed methods brief structured interviews exit survey performed explore barriers completing computer testing. Results: Of 791 potentially eligible patients (mean age 70 ± 14 years), there was low feasibility remote testing, only 401 (51%) the T-MoCA, 242 (31%) Creyos. Our regression models show that (OR T-MoCA : 0.95 (95% Confidence Interval (CI): 0.94–0.97); OR Creyos CI: 0.94–0.96)), functional (mRS 2–5; 0.55 0.37–0.81); 0.66 0.44–0.98)), life (EQ-VAS; 1.02 1.01–1.03); OR:1.02 1.01–1.03)) length hospital stay 0.98 0.96–0.99); 0.97 0.94–0.99)) predicted test completion; literacy 1.12 1.04–1.21)). In interviews, preference for accessibility reported. Discussion: has limited as secondary outcome in large acute stroke trials. who are older, worse life, or severe post-stroke less likely complete outcomes. Conclusion: Innovative approaches trials needed. Data Access available upon request.

Language: Английский

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