Nettle (Urtica dioica) supplementation: impact on growth, hematology, immune response, and resilience to Aeromonas hydrophila in Labeo rohita fingerlings DOI
Javed Ahmed Ujan, Asif Raza, Syed Sikandar Habib

et al.

Veterinary Research Communications, Journal Year: 2024, Volume and Issue: 49(1)

Published: Nov. 15, 2024

Language: Английский

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest DOI Creative Commons
Cátia Ferreira, Mafalda C. Sarraguça

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(1), P. 124 - 124

Published: Jan. 18, 2024

The extraction of bioactive compounds pharmaceutical interest from natural sources has been significantly explored in recent decades. However, the techniques used were not very efficient terms time and energy consumption; additionally, solvents for harmful environment. To improve environmental impact extractions at same increase yields, several new developed. Among most ones are ultrasound-assisted microwave-assisted extraction. These increased yield selectivity a smaller amount with decrease consumption. Nevertheless, high volume organic was still extraction, causing subsequent problem. Neoteric appeared as green alternatives to solvents. neoteric solvents, deep eutectic evidenced be one best due their intrinsic characteristics. considered because they made up such sugars, amino acids, carboxylic acids having low toxicity degradability. In addition, simple prepare, an atomic economy 100%, attractive physicochemical properties. Furthermore, huge number that can synthesize these make them useful since tailored selective towards specific component or class components. main aim this paper is give comprehensive review which describes properties, characteristics, production methods well its application extract interest. Additionally, overview more sustainable also given.

Language: Английский

Citations

55

Sustainable Valorization of Fruit and Vegetable Waste for Bioactive Compounds: Advancing Functional Food and Wellness DOI

Jibanjyoti Panda,

Rajshree Amrit,

Awdhesh Kumar Mishra

et al.

Waste and Biomass Valorization, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 9, 2025

Language: Английский

Citations

2

Ultrasound-assisted extraction with natural deep eutectic solvent for phenolic compounds recovery from Rosa damascene Mill.: Experimental design optimization using central composite design DOI
Hyrije Koraqi, Alev Yüksel Aydar, Waseem Khalid

et al.

Microchemical Journal, Journal Year: 2023, Volume and Issue: 196, P. 109585 - 109585

Published: Nov. 2, 2023

Language: Английский

Citations

31

Optimization of extraction condition to improve blackthorn (Prunus spinosa L.) polyphenols, anthocyanins and antioxidant activity by natural deep eutectic solvent (NADES) using the simplex lattice mixture design method DOI
Hyrije Koraqi, Alev Yüksel Aydar, R. Pandiselvam

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 200, P. 110497 - 110497

Published: April 6, 2024

Language: Английский

Citations

11

Evaluation of Bioactive Compounds and Chemical Elements in Herbs: Effectiveness of Choline Chloride-Based Deep Eutectic Solvents in Ultrasound-Assisted Extraction DOI Creative Commons
Aleksandra Szydłowska‐Czerniak,

Agnieszka Kowaluk,

Michał Strzelec

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 368 - 368

Published: Jan. 17, 2025

In this study, the effectiveness of three choline chloride (ChCl)-based deep eutectic solvents (DESs) formed using malonic acid (MalA), glycerol (Gly), and glucose (Glu) as hydrogen bond donors two conventional (50% methanol 50% ethanol) for ultrasonic-assisted extraction (UAE) antioxidant compounds from four herbs (chamomile, lemon balm, nettle, spearmint) were estimated. The capacity (AC) obtained herb extracts was determined by modified 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), cupric reducing (CUPRAC) methods. Profiles phenolic acids, flavonoid aglycones, glycosides in green quantitatively analyzed ultra-performance liquid chromatography (UPLC). Among prepared DESs, highest potential total contents achieved ChCl:MalA (1:1). Unexpectedly, selected extracted significantly lower amounts antioxidants investigated than alcohols. Additionally, macroelements (K, Na, Ca, Mg), micronutrients (Mn, Zn, Fe, Cu), a toxic element (Cd) inductively coupled plasma-mass spectrometry (ICP-MS). Determining compositions elements is essential understanding their nutritive importance when applied food, cosmetic, pharmaceutical industries.

Language: Английский

Citations

1

Bioactive Recovery from Watermelon Rind Waste Using Ultrasound-Assisted Extraction DOI Creative Commons
Sania Zia, Moazzam Rafiq Khan, Rana Muhammad Aadil

et al.

ACS Food Science & Technology, Journal Year: 2024, Volume and Issue: 4(3), P. 687 - 699

Published: Feb. 13, 2024

In response to the imperative address food and agricultural waste promote environmental sustainability, this study investigates transformation of watermelon rind into a valuable resource. We extract polyphenols antioxidants from freeze-dried across four cultivars (Crimson Sweet, Black Prince, Chairman, Sugar Baby) using ultrasound-assisted extraction. Solvent selection, based on preliminary experiment, was optimized through surface methodology (RSM), fine-tuning solvent concentration sonication time. The RSM effectively modeled our responses (R2 > 0.90), confirming its suitability for optimization. Applying parameters (80% 20 min sonication) rinds yielded extracts rich in flavanols (10–30 mg/g) phenolics (1–2.5 mg/g), with high DPPH (22–40 mg Trolox/g) FRAP (26–42 ferrous sulfate/g) antioxidant activities. Furthermore, fatty acid phytosterol profiles were reported, demonstrating their potential applications food, pharmaceuticals, nutraceuticals, industry.

Language: Английский

Citations

6

Exploration of novel eco-friendly techniques to utilize bioactive compounds from household food waste: special reference to food applications DOI Creative Commons
Farzana Siddique,

Zoha Ali,

Muhammad Sajid Arshad

et al.

Frontiers in Food Science and Technology, Journal Year: 2024, Volume and Issue: 4

Published: May 3, 2024

The issue of household waste management is a pervasive global concern. Household waste, especially food comprises reservoir compounds with potential economic value, among which bioactive prominently feature. These compounds, derived from natural chemical substances inherent in animal and protein sources, offer nutritional benefits. Extracted find versatile applications various domains including textiles, cosmetics, nutraceuticals, additives, the agriculture sector. extraction such achieved through diversity techniques, conventional methods alongside non-conventional green approaches as using enzymes, microwaves, or supercritical fluids. However, there an increasing need for sustainable approaches, leading to bioactive-rich extracts low environmental impact. This review thoroughly summarizes origins, kinds, characteristics chemicals found waste. It also addresses most promising innovative methodologies recovery functional materials that have been published recently. New technologies can meaningfully manage are valuable industrial applications.

Language: Английский

Citations

4

Optimization of UAE-NADES green extraction of bioactive compounds from chickpea (Cicer arietinum L.) sprouts using simplex lattice mixture design methodology DOI Creative Commons
Waseem Khalid, Hyrije Koraqi,

Imed E Benmebarek

et al.

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 112, P. 107186 - 107186

Published: Nov. 30, 2024

Language: Английский

Citations

3

Protective Effect of Urtica dioica Extract against Oxidative Stress in Human Skin Fibroblasts DOI Creative Commons
Agnieszka Skalska-Kamińska,

Weronika Wójciak,

Magdalena Żuk

et al.

Life, Journal Year: 2023, Volume and Issue: 13(11), P. 2182 - 2182

Published: Nov. 9, 2023

Urtica dioica is a species with well-established significance in folk medicine many countries. It was utilized to support the treatment of arthritis, allergies, and urinary tract disorders; however, substantial presence antioxidants suggests that nettle extract could also have positive impact on skin. The objective this study assess human skin fibroblasts subjected oxidative stress. Various solvents were tested prepare an rich polyphenolic compounds high antioxidant potential. chemical composition determined using ultra-high-performance liquid chromatography mass spectrometry (UPLC-DAD-MS). H2O2 used induce stress cell viability, metabolism evaluated through NR MTT assays. Our demonstrated extraction 80% ethanol, followed by drying re-dissolving pure water, more efficient than direct water. This yielded compounds, chlorogenic acid caffeoylmalic as predominant averaging 64.9 114.4 µg/mL, respectively. exhibited properties DPPH ABTS Furthermore, it did not exhibit cytotoxicity negatively affect metabolism. In addition, effectively reduced ROS H2O2-stimulated cells, at highest concentration tested, levels returned those untreated control. protected against H2O2-induced cytotoxicity. viability maintained level control when cells pretreated before exposure. These findings indicate U. valuable safe additive skincare products.

Language: Английский

Citations

7

Antioxidant and Anti-Inflammatory Effects of Nettle Polyphenolic Extract: Impact on Human Colon Cells and Cytotoxicity Against Colorectal Adenocarcinoma DOI Creative Commons
Magdalena Wójciak, Roman Paduch, Piotr Drozdowski

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(21), P. 5000 - 5000

Published: Oct. 22, 2024

L. is one of the most widely utilized medicinal plants commonly applied in form tea, juice, and dietary supplements. This study aimed to assess effect

Language: Английский

Citations

2